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Publication Details
AFRICAN RESEARCH NEXUS
SHINING A SPOTLIGHT ON AFRICAN RESEARCH
medicine
Assessment of
99
tc
m
-tetrofosmin lung uptake a modified method to avoid the contribution from high chest wall activity
Nuclear Medicine Communications, Volume 19, No. 9, Year 1998
Notification
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Description
Evaluation of lung uptake during routine 99Tcm-tetrofosmin myocardial SPET (single photon emission tomography) studies may be hindered by substantial chest muscle uptake, particularly post-exercise. This study investigated this proposal and analysed the various components of chest activity that may add to the real lung uptake. Exercise SPET studies were performed on normal subjects using 99Tcm-tetrofosmin and compared with the results of 99Tcm-tetrofosmin and 201T1 studies. The chest to heart count ratio (CHR) was calculated from the anterior SPET projection and further subclassified into lung, anterior chest and posterior chest to heart ratios (LHR, AHR, PHR) from the left anterior oblique (LAO) projection. On post-exercise images, the 99Tcm-tetrofosmin CHR was significantly higher than that of 201T1 and 99Tcm-tetrofosmin -sestamibi. Both the 99Tcm-tetrofosmin AHR and PHR were higher than those of 201T1 and 99Tcm-sestamibi. However, the LHR was similar for all three radiopharmaceuticals. In contrast, the rest 99Tcm-tetrofosmin images differed little from the 201T1 and 99Tcm-sestamibi ones. Thus, 99Tcm-tetrofosmin lung uptake post-exercise should be interpreted with caution, as chest muscle uptake is higher than normal. A more accurate evaluation of 99Tcm-tetrofosmin lung uptake is achieved from the LAO projection, where the contribution from chest muscle counts is much less than in the routinely used anterior projection. © 1998 Lippincott-Raven Publishers. © 1998 Lippincott-Raven Publishers.
Authors & Co-Authors
Heiba, Sherif I.
Kuwait, Kuwait City
Kuwait University
Ziada, Gaber A.
Kuwait, Kuwait City
Kuwait University
Higazy, Ezzat
Kuwait, Kuwait City
Kuwait University
Saleh, M.
Kuwait, Kuwait City
Kuwait University
Elgazzar, Abdelhamid Hamid H.
Kuwait, Kuwait City
Kuwait University
Statistics
Citations: 5
Authors: 5
Affiliations: 1
Identifiers
Doi:
10.1080/00006231-199809000-00006
ISSN:
01433636
e-ISSN:
14735628
Research Areas
Environmental