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Publication Details
AFRICAN RESEARCH NEXUS
SHINING A SPOTLIGHT ON AFRICAN RESEARCH
medicine
Neuroendocrinal study of Depression in male epileptic patients
Journal of Neuropsychiatry and Clinical Neurosciences, Volume 23, No. 2, Year 2011
Notification
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Description
Endocrine changes are reported in both epilepsy and depression. The interrelationships between mood, epilepsy, and endocrine changes are not well characterized. The authors included 40 epileptic patients (20 depressed, 20 nondepressed) and 20 healthy subjects. All patients had an electroencephalogram, and were given the Hamilton Rating Scale for Depression. All subjects were tested for serum levels of cortisol, prolactin, testosterone, and thyroid hormones. Patients were medication-free. Patients had elevated prolactin and cortisol and reduced serum testosterone relative to control subjects. Depressed patients had higher cortisol levels than nondepressed. Data suggest that the effects of epilepsy and depression on cortisol, but not other hormones, may be additive. © 2011 American Psychiatric Association.
Authors & Co-Authors
Afifi, Samah
United States, Detroit
Wayne State University School of Medicine
Fadel, Wael A.
Egypt, Tanta
Faculty of Medicine
Morad, Heba
United States, Detroit
Wayne State University School of Medicine
Eldod, Abdo
United States, Detroit
Wayne State University School of Medicine
Gad, Elsayed
United States, Detroit
Wayne State University School of Medicine
Arfken, Cynthia Lee
United States, Detroit
Wayne State University School of Medicine
Abou-Samra, Abdul Badi
United States, Detroit
Wayne State University School of Medicine
Boutros, Nash
United States, Detroit
Wayne State University School of Medicine
Statistics
Citations: 8
Authors: 8
Affiliations: 2
Identifiers
Doi:
10.1176/jnp.23.2.jnp163
ISSN:
08950172
e-ISSN:
15457222
Research Areas
Mental Health
Participants Gender
Male