Skip to content
Home
About Us
Resources
Profiles Metrics
Authors Directory
Institutions Directory
Top Authors
Top Institutions
Top Sponsors
AI Digest
Contact Us
Menu
Home
About Us
Resources
Profiles Metrics
Authors Directory
Institutions Directory
Top Authors
Top Institutions
Top Sponsors
AI Digest
Contact Us
Home
About Us
Resources
Profiles Metrics
Authors Directory
Institutions Directory
Top Authors
Top Institutions
Top Sponsors
AI Digest
Contact Us
Menu
Home
About Us
Resources
Profiles Metrics
Authors Directory
Institutions Directory
Top Authors
Top Institutions
Top Sponsors
AI Digest
Contact Us
Publication Details
AFRICAN RESEARCH NEXUS
SHINING A SPOTLIGHT ON AFRICAN RESEARCH
Aginoside saponin, a potent antifungal compound, and secondary metabolite analyses from Allium nigrum L.
Phytochemistry Letters, Volume 6, No. 2, Year 2013
Notification
URL copied to clipboard!
Description
The HPLC and spectral analyses of cysteine sulfoxides (CSOs), total polyphenols (TP), and total saponins revealed quantitative variations within the different organs of Allium nigrum L. A large accumulation of CSOs was detected in the bulb (0.367 mg/g fw), of TP in the leaf (116.05 mg CE/100 g fw), and of saponins in the root (19.38 mg/g dw). Phytochemical and chromatographical investigations of A. nigrum root extract led to the isolation of a spirostane-type glycoside or aginoside. The structure was elucidated by spectroscopic analysis (2D NMR, FABMS, HR-ESI-MS). The structure of the aginoside was identified as 25(R,S)-5α-spirostan-2α,3β,6β- trio1-3-O-β-d-glucopyranosyl-(1→2)-O-[β-d-xylopyranosyl- (1→3)]-O-β-d-glucopyranosyl-(1→4)-β-d-galactopyranoside. The highest content of aginoside, 2.9 mg/g dw, was detected in the root. The in vitro and in vivo antifungal activity of aginoside was evaluated for the first time against phytopathogens. This compound showed significant (P < 0.05) antifungal activity depending on the concentration. © 2013 Phytochemical Society of Europe. Published by Elsevier B.V. All rights reserved.
Authors & Co-Authors
Abdelrahman, Mostafa
Japan, Yamaguchi
Yamaguchi University
Japan, Tottori
Tottori University
Jogaiah, Sudisha
Japan, Yamaguchi
Yamaguchi University
India, Mysore
University of Mysore
El-Sayed, Magdi A.
Egypt, Aswan
Faculty of Science
Ito, Shinichi
Japan, Yamaguchi
Yamaguchi University
Japan, Tottori
Tottori University
Ikeda, Tsuyoshi
Japan, Kumamoto
Sojo University
Yamauchi, Naoki
Japan, Yamaguchi
Yamaguchi University
Japan, Tottori
Tottori University
Shigyo, Masayoshi
Japan, Yamaguchi
Yamaguchi University
Japan, Tottori
Tottori University
Statistics
Citations: 57
Authors: 7
Affiliations: 5
Identifiers
Doi:
10.1016/j.phytol.2013.03.001
e-ISSN:
18767486
Study Approach
Quantitative