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Publication Details
AFRICAN RESEARCH NEXUS
SHINING A SPOTLIGHT ON AFRICAN RESEARCH
medicine
An epidemiological study of stroke hospitalizations in maputo, mozambique: A high burden of disease in a resource-poor country
Stroke, Volume 41, No. 11, Year 2010
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Description
Background and Purpose: Already a major cause of death and disability in high-income countries, the burden of stroke in sub-Saharan Africa is also expected to be high. However, specific stroke data are scarce from resource-poor countries. We studied the incidence, characteristics, and short-term consequences of hospitalizations for stroke in Maputo, Mozambique. Methods: Over 12 months, comprehensive data from all local patients admitted to any hospital in Maputo with a new stroke event were prospectively captured according to the World Health Organization's STEPwise approach to stroke surveillance program. Disability levels (pre-and posthospital discharge) and short-term case-fatality (in-hospital and 28 days) were also studied. Results: Overall, 651 new stroke events (mean age 59.1±13.2 years and 53% men) were captured by the registry with 601 confirmed by CT scan (83.4%) or necropsy (8.9%). Crude and adjusted (world reference population) annual incidence rates of stroke were 148.7 per 100 000 and 260.1 per 100 000 aged 25 years, respectively. Of these, 531 (81.6%) represented a first-ever stroke event comprising 254 ischemic (42.0%) and 217 (36.1%) an intracerebral hemorrhage. Before admission, 561 patients (86.2%) had hypertension and 271 (41.6%) had symptoms for >24 hours. In-hospital and 28-day case-fatality were 33.3% and 49.6% (72.3% for hemorrhagic stroke), respectively. From almost no preadmission disability, 64.4% of 370 survivors at 28 days had moderate-to-severe disability. Conclusions: The burden of disease associated with stroke is high in Maputo, emphasizing the importance of primary prevention and improvement of the standards of care in a developing country under epidemiological transition. © 2010 American Heart Association, Inc.
Authors & Co-Authors
Damasceno, A. Antonio Moura
Mozambique, Maputo
Universidade Eduardo Mondlane
Gomes, Joana Costa
Portugal, Porto
Faculdade de Medicina da Universidade do Porto Fmup
Portugal, Porto
Universidade do Porto
Azevedo, Ana Raquel
Portugal, Porto
Faculdade de Medicina da Universidade do Porto Fmup
Portugal, Porto
Universidade do Porto
Carrilho, Carla
Mozambique, Maputo
Universidade Eduardo Mondlane
Lobo, Vitória
Mozambique, Maputo
Universidade Eduardo Mondlane
Lopes, Hélder
Mozambique, Maputo
Universidade Eduardo Mondlane
Madede, Tavares
Mozambique, Maputo
Universidade Eduardo Mondlane
Pravinrai, Pius
Mozambique, Maputo
Universidade Eduardo Mondlane
Silva-Matos, Carla
Mozambique, Maputo
Ministry of Health Mozambique
Jalla, Sulemane
Mozambique, Maputo
Universidade Eduardo Mondlane
Stewart, Simon D.
Australia, Melbourne
Baker Heart and Diabetes Institute
Lunet, Nuno
Portugal, Porto
Faculdade de Medicina da Universidade do Porto Fmup
Portugal, Porto
Universidade do Porto
Statistics
Citations: 98
Authors: 12
Affiliations: 5
Identifiers
Doi:
10.1161/STROKEAHA.110.594275
ISSN:
00392499
Research Areas
Disability
Health System And Policy
Noncommunicable Diseases
Study Design
Cross Sectional Study
Cohort Study
Study Locations
Mozambique
Participants Gender
Male