Skip to content
Home
About Us
Resources
Profiles Metrics
Authors Directory
Institutions Directory
Top Authors
Top Institutions
Top Sponsors
AI Digest
Contact Us
Menu
Home
About Us
Resources
Profiles Metrics
Authors Directory
Institutions Directory
Top Authors
Top Institutions
Top Sponsors
AI Digest
Contact Us
Home
About Us
Resources
Profiles Metrics
Authors Directory
Institutions Directory
Top Authors
Top Institutions
Top Sponsors
AI Digest
Contact Us
Menu
Home
About Us
Resources
Profiles Metrics
Authors Directory
Institutions Directory
Top Authors
Top Institutions
Top Sponsors
AI Digest
Contact Us
Publication Details
AFRICAN RESEARCH NEXUS
SHINING A SPOTLIGHT ON AFRICAN RESEARCH
Prevalence of depression and validation of the beck depression inventory-II and the children's depression inventory-short amongst HIV-positive adolescents in Malawi
Journal of the International AIDS Society, Volume 17, Article 18965, Year 2014
Notification
URL copied to clipboard!
Description
Introduction: There is a remarkable dearth of evidence on mental illness in adolescents living with HIV/AIDS, particularly in the African setting. Furthermore, there are few studies in sub-Saharan Africa validating the psychometric properties of diagnostic and screening tools for depression amongst adolescents. The primary aim of this cross-sectional study was to estimate the prevalence of depression amongst a sample of HIV-positive adolescents in Malawi. The secondary aim was to develop culturally adapted Chichewa versions of the Beck Depression Inventory-II (BDI-II) and Children's Depression Inventory-II-Short (CDI-II-S) and conduct a psychometric evaluation of these measures by evaluating their performance against a structured depression assessment using the Children's Rating Scale, Revised (CDRS-R). Study design: Cross-sectional study. Methods: We enrolled 562 adolescents, 12-18 years of age from two large public HIV clinics in central and southern Malawi. Participants completed two self-reports, the BDI-II and CDI-II-S, followed by administration of the CDRS-R by trained clinicians. Sensitivity, specificity and positive and negative predictive values for various BDI-II and CDI-II-S cut-off scores were calculated with receiver operating characteristics analysis. The area under the curve (AUC) was also calculated. Internal consistency was measured by standardized Cronbach's alpha coefficient, and correlation between self-reports and CDRS-R by Spearman's correlation. Results: Prevalence of depression as measured by the CDRS-R was 18.9%. Suicidal ideation was expressed by 7.1% (40) using the BDI-II. The AUC for the BDI-II was 0.82 (95% CI 0.78-0.89) and for the CDI-II-S was 0.75 (95% CI 0.70-0.80). A score of ≥13 in BDI-II achieved sensitivity of >80%, and a score of ≥17 had a specificity of >80%. The Cronbach's alpha was 0.80 (BDI-II) and 0.66 (CDI-II-S). The correlation between the BDI-II and CDRS-R was 0.42 (p <0.001) and between the CDI-II-S and CDRS-R was 0.37 (p<0.001). Conclusions: This study demonstrates that the BDI-II has sound psychometric properties in an outpatient setting among HIV-positive adolescents in Malawi. The high prevalence of depression amongst HIV-positive Malawian adolescents noted in this study underscores the need for the development of comprehensive services for HIV-positive adolescents. © 2014 Kim MH et al; licensee International AIDS Society.
Authors & Co-Authors
Kim, Maria H.
United States, Houston
Texas Children's Hospital
Malawi, Lilongwe
Baylor College of Medicine-abbott Fund Children's Clinical Center of Excellence
Mazenga, Alick C.
Malawi, Lilongwe
Baylor College of Medicine-abbott Fund Children's Clinical Center of Excellence
Devandra, Akash
United States, Houston
Texas Children's Hospital
Ahmed, Saeed
United States, Houston
Texas Children's Hospital
Kazembe, Peter Nicholas
Malawi, Lilongwe
Baylor College of Medicine-abbott Fund Children's Clinical Center of Excellence
Yu, Xiaoying
United States, Houston
Baylor College of Medicine
Nguyen, Chi
United States, Houston
Baylor College of Medicine
Sharp, Carla
United States, Houston
University of Houston
Statistics
Citations: 92
Authors: 8
Affiliations: 4
Identifiers
Doi:
10.7448/IAS.17.1.18965
e-ISSN:
17582652
Research Areas
Infectious Diseases
Maternal And Child Health
Mental Health
Study Design
Cross Sectional Study
Study Approach
Quantitative
Study Locations
Malawi