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Publication Details
AFRICAN RESEARCH NEXUS
SHINING A SPOTLIGHT ON AFRICAN RESEARCH
biochemistry, genetics and molecular biology
Quantitative measurement of cutaneous perception in diabetic neuropathy
Muscle & Nerve, Volume 18, No. 6, Year 1995
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Description
To determine the diagnostic value of various cutaneous sensory modalities in diabetic neuropathy, we studied cutaneous perception at the dominant hallux of 113 subjects (32 normal healthy controls and 81 diabetic subjects). The cutaneous sensory perception tests included warm and cold thermal perception, vibration, touch‐pressure sensation, and current perception testing (CPT). The sensitivity of each modality when specificity is held greater than 90% was as follows: warm = 78%, cold = 77%, vibration = 88%, tactile‐pressure = 77%, 5‐Hz CPT = 52%, 250‐Hz CPT = 48%, and 2000‐Hz CPT = 56%. Combination thermal and vibratory gave optimum sensitivity (92–95%) and specificity (77–86%). We conclude that vibratory and thermal testing should be the primary screening tests for diabetic peripheral neuropathy. Other modalities may be of use only in specific situations. © 1995 John Wiley & Sons, Inc. Copyright © 1995 John Wiley & Sons, Inc.
Authors & Co-Authors
Vinik, Aaron I.
United States, Norfolk
Diabetes Institutes Foundation
United States, Norfolk
Eastern Virginia Medical School
Stansberry, Kevin B.
United States, Norfolk
Diabetes Institutes Foundation
Statistics
Citations: 145
Authors: 2
Affiliations: 2
Identifiers
Doi:
10.1002/mus.880180603
ISSN:
0148639X
Study Approach
Quantitative