Skip to content
Home
About Us
Resources
Profiles Metrics
Authors Directory
Institutions Directory
Top Authors
Top Institutions
Top Sponsors
AI Digest
Contact Us
Menu
Home
About Us
Resources
Profiles Metrics
Authors Directory
Institutions Directory
Top Authors
Top Institutions
Top Sponsors
AI Digest
Contact Us
Home
About Us
Resources
Profiles Metrics
Authors Directory
Institutions Directory
Top Authors
Top Institutions
Top Sponsors
AI Digest
Contact Us
Menu
Home
About Us
Resources
Profiles Metrics
Authors Directory
Institutions Directory
Top Authors
Top Institutions
Top Sponsors
AI Digest
Contact Us
Publication Details
AFRICAN RESEARCH NEXUS
SHINING A SPOTLIGHT ON AFRICAN RESEARCH
biochemistry, genetics and molecular biology
Ten-year results utilizing chemotherapy as primary treatment in nonmetastatic, rapidly progressing breast cancer
Cancer Investigation, Volume 11, No. 4, Year 1993
Notification
URL copied to clipboard!
Description
Eighty-three patients with rapidly progressing breast cancer (RPBC) were entered into a study of primary chemotherapy (cyclophosphamide, methotrexate, and 5-fluorouracil) and subsequent randomization to surgery or radiotherapy for control of local/regional disease. Eighty-three of these patients with redness, warmth, and edema compatible with clinical (inflammatory breast cancer) served as the focus for our analysis of factors associated with improved survival. The stage-specific disease-free intervals (DPI) of 36 and 21 months were substantially longer than in the earlier series (26 and 16 months) from the same institution. The evaluation of individual prognostic indicators revealed that the initial tumor size and the initial response to chemotherapy were the two independent factors most important in predicting the DPI. The continuing unmaintained 1-year remission in at least 12 patients supports the rationale for aggressive therapy in RPBC or (inflammatory breast cancer.). © 1993 Informa UK Ltd All rights reserved: reproduction in whole or part not permitted.
Authors & Co-Authors
Mourali, Nejib
Tunisia, Tunis
Institut Salah Azaiez de Tunis
Tabbane, Françoise
Tunisia, Tunis
Institut Salah Azaiez de Tunis
Muenz, Larry R.
United States, Rockville
National Cancer Institute Nci
Behi, Jacqueline
Tunisia, Tunis
Institut Salah Azaiez de Tunis
Moussa, Francoise Ben
Tunisia, Tunis
Institut Salah Azaiez de Tunis
Jaziri, Michèle
Tunisia, Tunis
Institut Salah Azaiez de Tunis
Levine, Paul H.
United States, Rockville
National Cancer Institute Nci
Statistics
Citations: 35
Authors: 7
Affiliations: 2
Identifiers
Doi:
10.3109/07357909309018867
ISSN:
07357907
Research Areas
Cancer
Health System And Policy
Study Design
Randomised Control Trial