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Publication Details
AFRICAN RESEARCH NEXUS
SHINING A SPOTLIGHT ON AFRICAN RESEARCH
medicine
RISK FACTORS FOR HUMAN IMMUNODEFICIENCY VIRUS SEROPOSITIVITY AMONG CHILDREN 1-24 MONTHS OLD IN KINSHASA, ZAIRE
The Lancet, Volume 328, No. 8508, Year 1986
Notification
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Description
A prevalence study of antibody to human immunodeficiency virus (HIV) was conducted in Kinshasa, Zaïre, among 258 children 2-24 months old who were in hospital, 191 children 1-20 months old who were attending a well-child clinic, and their mothers. 8 % of the mothers of both groups of children were seropositive. Among children under 9 months old, 12 of 102 (12%) hospital inpatients and 11 of 136 (8%) clinic attenders were seropositive, while in the 9-24-month age group 20 of 156 (13%) hospital children and only 1 of 55 (2%) clinic children were seropositive (Fisher's exact test, p = 0.01). 61 % of the seropositive children had seropositive mothers, indicating a high rate of vertical transmission. Factors associated with seropositivity among hospital children with seronegative mothers included male sex, increased lifetime number of medical injections, and previous blood transfusion or hospital admission. Among children who had not previously been transfused or admitted to hospital the seropositives had received more medical injections than the seronegatives (median 34.5 versus 14.5; Wilcoxon rank sum test, p = 0.006). HIV infection accounted for or complicated a substantial proportion of hospital paediatric admissions. Public health measures are urgently required to prevent parenteral and vertical transmission of HIV to infants and young children in Kinshasa. © 1986.
Authors & Co-Authors
Mann, Jonathan M.
Zaire
Projet Sida
United States, Atlanta
National Center for Infectious Diseases
Davachi, Farzin
Democratic Republic Congo, Kinshasa
Mama Yemo Hospital
Quinn, Thomas Charles
United States, Bethesda
National Institute of Allergy and Infectious Diseases Niaid
Bosenge, Ngaly
Zaire
Projet Sida
Piot, Peter K.
Belgium, Antwerpen
Prins Leopold Instituut Voor Tropische Geneeskunde
Asila, Pangu Kaza
Unknown Affiliation
Francis, Henry L.
Zaire
Projet Sida
United States, Bethesda
National Institute of Allergy and Infectious Diseases Niaid
Baudoux, P.
Democratic Republic Congo, Kinshasa
Mama Yemo Hospital
Nzilambi, Nzila E.
Zaire
Projet Sida
Colebunders, Robert Leon
Belgium, Antwerpen
Prins Leopold Instituut Voor Tropische Geneeskunde
Kabote, N.
Democratic Republic Congo, Kinshasa
Mama Yemo Hospital
Malonga, Miatudila
Unknown Affiliation
Curran, James W.
United States, Atlanta
National Center for Infectious Diseases
Statistics
Citations: 109
Authors: 13
Affiliations: 5
Identifiers
Doi:
10.1016/S0140-6736(86)90167-4
ISSN:
01406736
Research Areas
Health System And Policy
Infectious Diseases
Maternal And Child Health
Study Design
Cross Sectional Study
Participants Gender
Male