Skip to content
Home
About Us
Resources
Profiles Metrics
Authors Directory
Institutions Directory
Top Authors
Top Institutions
Top Sponsors
AI Digest
Contact Us
Menu
Home
About Us
Resources
Profiles Metrics
Authors Directory
Institutions Directory
Top Authors
Top Institutions
Top Sponsors
AI Digest
Contact Us
Home
About Us
Resources
Profiles Metrics
Authors Directory
Institutions Directory
Top Authors
Top Institutions
Top Sponsors
AI Digest
Contact Us
Menu
Home
About Us
Resources
Profiles Metrics
Authors Directory
Institutions Directory
Top Authors
Top Institutions
Top Sponsors
AI Digest
Contact Us
Publication Details
AFRICAN RESEARCH NEXUS
SHINING A SPOTLIGHT ON AFRICAN RESEARCH
Pharmaceutical potential of a fucoidan-like sulphated polysaccharide isolated from Halodule pinifolia
International Journal of Biological Macromolecules, Volume 62, Year 2013
Notification
URL copied to clipboard!
Description
In continuation with the screening of biological properties of seagrasses, we isolated sulphated polysaccharides from Halodule pinifolia. This is the first report that indicates the presence of fucoidan-like H. pinifolia crude sulphated polysaccharide (HPCSP) that are commonly found in brown algae being present in marine angiosperms. Fucoidan-like structures such as β-mannuronic acid residues and sulphate groups were confirmed by Fourier transform infrared (FTIR) spectral analysis. There was a high content of uronic acid. The isolated HPCSP consisted mainly of total sugar (54.17%), protein (11.06%), carbon (18.25%), nitrogen (1.77%), hydrogen (3.62%), C/N ratio (2.04%) and uronic acid (2.61%). This isolated HPCSP was further investigated to determine anticoagulant and antioxidant activity. The HPCSP had high activity in the total antioxidant assay (125.86mg ascorbic acid equivalents/g), DPPH radical scavenging rate (IC50 value 2.024±0.12μg/mL), deoxyribose radical scavenging rate (51.82% at 1000μg/mL) and H2O2 radical scavenging rate (IC50 value 6.904±0.34μg/mL). In the anticoagulant assay, prolonged clotting time was observed with application of HPCSP with increasing concentrations. Further purification and characterization process is underway to confirm the structures of HPCSP. From the observed results, this fucoidan-like HPCSP could be developed as a new natural source of potential antioxidants in the functional food industry. © 2013 Elsevier B.V.
Authors & Co-Authors
Rengasamy, Kannan R.R.
India, Chidambaram
Annamalai University
South Africa, Durban
University of Kwazulu-natal
Arumugam, Radjassegarin
India, Chidambaram
Annamalai University
India, Mayiladuthurai
A.v.c. College Autonomous
Anantharaman, Perumal
India, Chidambaram
Annamalai University
Statistics
Citations: 25
Authors: 3
Affiliations: 3
Identifiers
Doi:
10.1016/j.ijbiomac.2013.08.005
e-ISSN:
18790003
Research Areas
Environmental
Food Security