Ethynylferrocene-NiO/MWCNT nanocomposite modified carbon paste electrode as a novel voltammetric sensor for simultaneous determination of glutathione and acetaminophen

In the present study, the use of a carbon paste electrode modified by ethynylferrocene (EF) and NiO/MWCNT nanocomposite prepared by a simple and rapid method was described. The modified electrode showed an excellent character for electrocatalytic oxidization of glutathione (GSH) and acetaminophen (AC). For the mixture containing GSH and AC, the peaks potential well separated from each other. Their square wave voltammetrics peaks current increased linearly with their concentration at the ranges of 0.01-200 and 0.8-600 μM, respectively with the detection limits of 0.006 and 0.5 μM, respectively. The modified electrode was successfully used for the determination of the analytes in real samples with satisfactory results. © 2012 Elsevier B.V. All rights reserved.