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Publication Details
AFRICAN RESEARCH NEXUS
SHINING A SPOTLIGHT ON AFRICAN RESEARCH
arts and humanities
An evolving perspective about the origins of childhood undernutrition and nutritional interventions that includes the gut microbiome
Annals of the New York Academy of Sciences, Volume 1332, No. 1, Year 2014
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Description
The Sackler Institute for Nutrition Science and the World Health Organization (WHO) have worked together to formulate a research agenda for nutrition science. Undernutrition of children has profound effects on health, development, and achievement of full human capacity. Undernutrition is not simply caused by a lack of food, but results from a complex interplay of intra- and intergenerational factors. Representative preclinical models and comprehensive well-controlled longitudinal clinical studies are needed to further understand the contributions and the interrelationships among these factors and to develop interventions that are effective and durable. This paper summarizes work on mechanisms underlying the varied manifestations of childhood undernutrition and discusses current gaps in knowledge and challenges to our understanding of undernutrition and infection/immunity throughout the human life cycle, focusing on early childhood growth. It proposes a series of basic and clinical studies to address this global health challenge. © 2014 New York Academy of Sciences.
Authors & Co-Authors
Ahmed, Tahmeed J.
Bangladesh, Dhaka
International Centre for Diarrhoeal Disease Research Bangladesh
Berkley, James A.
Kenya, Nairobi
Wellcome Trust Research Laboratories Nairobi
Black, Robert E.
United States, Baltimore
Johns Hopkins University
Hossain, Muttaquina E.
Bangladesh, Dhaka
International Centre for Diarrhoeal Disease Research Bangladesh
Gordon, Jeffrey I.
United States, St. Louis
Washington University School of Medicine in St. Louis
Statistics
Citations: 43
Authors: 5
Affiliations: 6
Identifiers
Doi:
10.1111/nyas.12487
ISSN:
00778923
Research Areas
Food Security
Maternal And Child Health
Study Design
Cohort Study