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Publication Details
AFRICAN RESEARCH NEXUS
SHINING A SPOTLIGHT ON AFRICAN RESEARCH
medicine
The etiology of infectious corneal ulceration in Sierra Leone
International Ophthalmology, Volume 30, No. 6, Year 2010
Notification
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Description
The microbial etiology of infectious corneal ulceration in Sierra Leone has been investigated. Patients either presenting to district health centers or encountered on rural surveillance expeditions with suspected infectious ulcerative keratitis were recruited into the study. Infectious corneal ulceration was defined as clinical evidence of corneal infection with epithelial defect with or without hypopyon. Cultures were obtained in a standard fashion and subsequent microbial analysis performed on all specimens. Seventy-three (73) cases of suspected infectious ulcerative keratitis were obtained between January 2005 and January 2006. The most commonly isolated organisms from microbial cultures of infected eyes were Gram-negative bacteria (45.2%), Gram-positive bacteria (37.0%), and fungal species (35.6%). Mixed bacterial and fungal organisms were isolated from ten eyes (13.7%) and no organisms were isolated from four eyes (5.5%). There is a high incidence of Gram-negative and fungal ulcerative keratitis in the population studied in Sierra Leone. Empirical therapy for corneal ulceration in this region should be aimed towards treatment of bacterial, fungal, and mixed infections. © Springer Science+Business Media B.V. 2010.
Authors & Co-Authors
Capriotti, Joseph A.
United States, New York
New York Eye and Ear Infirmary of Mount Sinai
Pelletier, Jesse S.
United States, New York
New York Eye and Ear Infirmary of Mount Sinai
United States, Miami Beach
Ocean Ophthalmology Group
Shah, Mahendra K.
United States, New York
New York Eye and Ear Infirmary of Mount Sinai
Caivano, D. M.
United States, New York
Icahn School of Medicine at Mount Sinai
Turay, Patrick E.
Sierra Leone, Makeni
Holy Spirit Hospital
Ritterband, David Carl
United States, New York
New York Eye and Ear Infirmary of Mount Sinai
Statistics
Citations: 9
Authors: 6
Affiliations: 4
Identifiers
Doi:
10.1007/s10792-010-9348-1
ISSN:
01655701
Study Design
Cross Sectional Study
Cohort Study
Study Locations
Sierra Leone