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Publication Details
AFRICAN RESEARCH NEXUS
SHINING A SPOTLIGHT ON AFRICAN RESEARCH
agricultural and biological sciences
Urine heme dipsticks are useful in monitoring the impact of Praziquantel treatment on Schistosoma haematobium in sentinel communities of Delta State, Nigeria
Acta Tropica, Volume 122, No. 1, Year 2012
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Description
Nigeria is highly endemic for infection with Schistosoma haematobium, which most commonly manifests itself with blood in urine. To monitor the impact of annual mass drug administration (MDA) with Praziquantel for S. haematobium in Delta State, Nigeria, cross-sectional hematuria surveys of school children were conducted in 8 sentinel villages (SVs) at baseline (n= 240) and after two annual doses (n= 402). We assessed the comparability of three assessments of hematuria (child's reported history, nurse visual diagnosis (NVD) and dipstick) to determine the need for mass treatment. Dipstick was considered to be the gold standard. Prior to treatment, history and NVD each identified only the 3 most highly prevalent SVs, and overall this represented just 37.5% of the 8 SVs in need of treatment. Following treatment, after dipstick prevalence decreased by 88.5% (p< 0.001), and history and NVD identified only one of two villages still needing treatment. The study suggests that dipsticks should be the recommended method for launching and monitoring mass treatment for S. haematobium. © 2012.
Authors & Co-Authors
Emukah, Emmanuel C.
United States, Atlanta
The Carter Center
Gutman, Julie R.
United States, Atlanta
Children's Healthcare of Atlanta at Egleston
Eguagie, John
United States, Atlanta
The Carter Center
Miri, Emmanuel S.
United States, Atlanta
The Carter Center
Yinkore, Paul
Nigeria, Asaba
Ministry of Health
Okocha, Ndudi
Nigeria, Asaba
Ministry of Health
Jibunor, Victoria
Nigeria, Asaba
Ministry of Health
Nebe, Obiageli Josephine
Nigeria, Abuja
Federal Ministry of Health
Nwoye, Augustine Ikenna
Nigeria, Abuja
Federal Ministry of Health
Richards, Frank O.
United States, Atlanta
The Carter Center
Statistics
Citations: 28
Authors: 10
Affiliations: 4
Identifiers
Doi:
10.1016/j.actatropica.2012.01.002
ISSN:
0001706X
e-ISSN:
18736254
Research Areas
Health System And Policy
Maternal And Child Health
Study Design
Cross Sectional Study
Study Locations
Nigeria