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Publication Details
AFRICAN RESEARCH NEXUS
SHINING A SPOTLIGHT ON AFRICAN RESEARCH
medicine
Assessment of serum 25-hydroxyvitamin D levels in children with atopic dermatitis: Correlation with SCORAD index
Dermatitis, Volume 24, No. 6, Year 2013
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Description
Background: Atopic dermatitis (AD) is a chronic inflammatory skin disorder with an immunologic basis. It may have negative medical and social impacts on a patient and his family. Objectives: To assess serum level of vitamin D among children with AD and determine its association with AD severity using the AD Scoring System Index. Study Design: A case-control study. Patients and Methods: Twenty-nine patients with AD in the age group between 2 and 12 years were enrolled in the study. The severity of the disease was determined by the AD scoring system. Thirty controls were recruited. Serum levels of 25-hydroxyvitamin D3 [25(OH)D3] were tested using commercial automated chemiluminescent microparticle immunoassay. Results: The mean value of vitamin D in children with AD was much lower than normal value, and there was a significant difference in the mean values of vitamin D between children with AD (5.4±1.9 ng/mL) and the controls (28.9±2.4 ng/mL). Serum 25(OH)D levels were found to be significantly higher in mild AD (14.6±3.5 ng/mL) compared with moderate (5.5±3.1 ng/mL) or severe AD (0.3±0.1 ng/mL); P<0.001. Conclusion: Patients with AD have lower serum vitamin D levels than normal. Vitamin D deficiency might be related to the severity of AD. © 2013 by the American Contact Dermatitis Society.
Authors & Co-Authors
El-Taieb, M. A.
Egypt, Qena
South Valley University
Fayed, Hanan M.
Egypt, Qena
Faculty of Medicine
Aly, Sanaa Shaker
Egypt, Qena
Faculty of Medicine
Ibrahim, Ahmed K.
Egypt, Asyut
Faculty of Medicine
Statistics
Citations: 55
Authors: 4
Affiliations: 3
Identifiers
Doi:
10.1097/DER.0000000000000010
ISSN:
17103568
Research Areas
Health System And Policy
Maternal And Child Health
Study Design
Case-Control Study