Skip to content
Home
About Us
Resources
Profiles Metrics
Authors Directory
Institutions Directory
Top Authors
Top Institutions
Top Sponsors
AI Digest
Contact Us
Menu
Home
About Us
Resources
Profiles Metrics
Authors Directory
Institutions Directory
Top Authors
Top Institutions
Top Sponsors
AI Digest
Contact Us
Home
About Us
Resources
Profiles Metrics
Authors Directory
Institutions Directory
Top Authors
Top Institutions
Top Sponsors
AI Digest
Contact Us
Menu
Home
About Us
Resources
Profiles Metrics
Authors Directory
Institutions Directory
Top Authors
Top Institutions
Top Sponsors
AI Digest
Contact Us
Publication Details
AFRICAN RESEARCH NEXUS
SHINING A SPOTLIGHT ON AFRICAN RESEARCH
medicine
Langerhans-cell histiocytosis of the orbit. A case study
Journal Francais d'Ophtalmologie, Volume 28, No. 8, Year 2005
Notification
URL copied to clipboard!
Description
Purpose: Langerhans' cell histiocytosis is a rare disease representing less than 1% of orbital tumors. Methods: We report a case of Langerhans cell histiocytosis with orbital involvement in a 9-year-old boy. He presented with an inflammatory swelling if the left lateral orbital wall. The computed tomographic scan revealed an orbital cellular mass with lytic bone lesion within the orbital roof and intracranial enlargement. Results: The cytological study after a biopsy showed infiltrates of histiocytes derived from Langerhans cells. Diagnosis was confirmed by immunohistochemistry, which identified positive staining with anti-S100 and anti-CD1a antibodies. The rapidly expanding orbital tumor, posing a threat of ocular compression as well as intracranial spreading, was treated by chemotherapy (Vinblastine) combined with a steroid. Conclusion: A 2-year follow-up showed no evidence of recurrence or systemic involvement. According to this observation, the authors describe the clinicopathological and histological features of orbital involvement in Langerhans cell histiocytosis. © Masson, Paris, 2005.
Authors & Co-Authors
Chefchaouni, Mohammed Charif
Morocco, Rabat
University Hospital Rabat-salé
Lahlou, L.
Morocco, Rabat
University Hospital Rabat-salé
Hajji, Zakia
Morocco, Rabat
University Hospital Rabat-salé
Chaoui, Z.
Morocco, Rabat
University Hospital Rabat-salé
El-Khorassani, Mohammed
Morocco, Rabat
University Hospital Rabat-salé
Alaoui, F. Msefer
Morocco, Rabat
University Hospital Rabat-salé
Berraho, Amina
Morocco, Rabat
University Hospital Rabat-salé
Statistics
Citations: 7
Authors: 7
Affiliations: 1
Identifiers
Doi:
10.1016/s0181-5512(05)81006-x
ISSN:
01815512
Research Areas
Cancer
Study Design
Cohort Study
Case Study
Study Approach
Qualitative
Participants Gender
Male