Skip to content
Home
About Us
Resources
Profiles Metrics
Authors Directory
Institutions Directory
Top Authors
Top Institutions
Top Sponsors
AI Digest
Contact Us
Menu
Home
About Us
Resources
Profiles Metrics
Authors Directory
Institutions Directory
Top Authors
Top Institutions
Top Sponsors
AI Digest
Contact Us
Home
About Us
Resources
Profiles Metrics
Authors Directory
Institutions Directory
Top Authors
Top Institutions
Top Sponsors
AI Digest
Contact Us
Menu
Home
About Us
Resources
Profiles Metrics
Authors Directory
Institutions Directory
Top Authors
Top Institutions
Top Sponsors
AI Digest
Contact Us
Publication Details
AFRICAN RESEARCH NEXUS
SHINING A SPOTLIGHT ON AFRICAN RESEARCH
medicine
The HAART cell phone adherence trial (WelTel Kenya1): A randomized controlled trial protocol
Trials, Volume 10, Article 87, Year 2009
Notification
URL copied to clipboard!
Description
Background: The objectives are to compare the effectiveness of cell phone-supported SMS messaging to standard care on adherence, quality of life, retention, and mortality in a population receiving antiretroviral therapy (ART) in Nairobi, Kenya. Methods and Design: A multi-site randomized controlled open-label trial. A central randomization centre provided opaque envelopes to allocate treatments. Patients initiating ART at three comprehensive care clinics in Kenya will be randomized to receive either a structured weekly SMS ('short message system' or text message) slogan (the intervention) or current standard of care support mechanisms alone (the control). Our hypothesis is that using a structured mobile phone protocol to keep in touch with patients will improve adherence to ART and other patient outcomes. Participants are evaluated at baseline, and then at six and twelve months after initiating ART. The care providers keep a weekly study log of all phone based communications with study participants. Discussion: Primary outcomes are self-reported adherence to ART and suppression of HIV viral load at twelve months scheduled follow-up. Secondary outcomes are improvements in health, quality of life, social and economic factors, and retention on ART. Primary analysis is by 'intention-to-treat'. Sensitivity analysis will be used to assess per-protocol effects. Analysis of covariates will be undertaken to determine factors that contribute or deter from expected and determined outcomes. Trial Registration: This study protocol tests whether a novel structured mobile phone intervention can positively contribute to ART management in a resource-limited setting. © 2009 Lester et al; licensee BioMed Central Ltd.
Authors & Co-Authors
Lester, Richard T.
Kenya, Nairobi
University of Nairobi
Canada, Winnipeg
University of Manitoba
Mills, Edward J.
Canada, Vancouver
The University of British Columbia
Kariri, Anthony
Kenya, Nairobi
University of Nairobi
Ritvo, Paul G.
Canada, Toronto
York University
Chung, Michael Hoonbae
United States, Washington, D.c.
Georgetown University
Jack, William
United States, Seattle
University of Washington
Habyarimana, James P.
United States, Seattle
University of Washington
Karanja, Sarah
Kenya, Nairobi
University of Nairobi
Barasa, Samson
Kenya, Nairobi
University of Nairobi
Nguti, Rosemary
Kenya, Nairobi
University of Nairobi
Estambale, Benson B.A.
Kenya, Nairobi
University of Nairobi College of Health Sciences
Ngugi, Elizabeth N.
Kenya, Nairobi
University of Nairobi
Ball, Terry Blake
Canada, Winnipeg
University of Manitoba
Thabane, Lehana
Canada, Hamilton
Mcmaster University
Kimani, Joshua
Kenya, Nairobi
University of Nairobi
Canada, Winnipeg
University of Manitoba
Gelmon, Lawrence J.
Kenya, Nairobi
University of Nairobi
Canada, Winnipeg
University of Manitoba
Ackers, Marta Louise
United States, Atlanta
Centers for Disease Control and Prevention
Plummer, Francis Allan
Canada, Winnipeg
University of Manitoba
Canada, Winnipeg
National Microbiology Laboratory
Statistics
Citations: 98
Authors: 18
Affiliations: 10
Identifiers
Doi:
10.1186/1745-6215-10-87
ISSN:
17456215
e-ISSN:
17456215
Research Areas
Disability
Health System And Policy
Infectious Diseases
Study Design
Randomised Control Trial
Cross Sectional Study
Cohort Study
Study Approach
Quantitative
Study Locations
Kenya