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Publication Details
AFRICAN RESEARCH NEXUS
SHINING A SPOTLIGHT ON AFRICAN RESEARCH
immunology and microbiology
Simple questionnaire and urine reagent strips compared to microscopy for the diagnosis of Schistosoma haematobium in a community in northern Ghana
Tropical Medicine and International Health, Volume 17, No. 10, Year 2012
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Description
Objectives To evaluate the utility of a simple questionnaire and urine reagent strip testing for the rapid diagnosis of Schistosoma haematobium in rural northern Ghana. Methods Cross-sectional parasitological and questionnaire survey in a community in northern Ghana. Participants provided two urine specimens that were examined under a microscope using a centrifugation method. The first urine sample was additionally subjected to reagent strip testing. A short questionnaire was administered to all participants. Results Microscopy of urine samples obtained from 208 individuals aged 1-77years revealed an S. haematobium prevalence of 6.8%. The presence of any blood or protein on a urine reagent strip was 100% and 42% sensitive, and 93% and 80% specific for S. haematobium diagnosis. Questionnaires were completed by 198 individuals. Self-reported haematuria showed a sensitivity of 53% and a specificity of 85%. A dichotomous two-question panel was helpful in S. haematobium diagnosis, with working and playing near the river significantly associated with S. haematobium infection (P<0.001). Conclusion The use of urine reagent strips, coupled with questions pertaining to water contact patterns, might be considered for point-of-contact diagnosis of S. haematobium where microscopy is unavailable. © 2012 Blackwell Publishing Ltd.
Authors & Co-Authors
Bogoch, Isaac Israel
Canada, Toronto
University Health Network University of Toronto
United States, Boston
Massachusetts General Hospital
United States, Boston
Harvard Medical School
Andrews, Jason Randolph
United States, Boston
Massachusetts General Hospital
United States, Boston
Harvard Medical School
Ephraim, Richard K.Dadzie
Ghana, Kumasi
Tamale Teaching Hospital
Utzinger, Jürg
Switzerland, Allschwil
Swiss Tropical and Public Health Institute Swiss Tph
Switzerland, Basel
Universitat Basel
Statistics
Citations: 40
Authors: 4
Affiliations: 6
Identifiers
Doi:
10.1111/j.1365-3156.2012.03054.x
ISSN:
13602276
e-ISSN:
13653156
Research Areas
Environmental
Study Design
Cross Sectional Study
Study Approach
Quantitative
Study Locations
Ghana