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AFRICAN RESEARCH NEXUS

SHINING A SPOTLIGHT ON AFRICAN RESEARCH

biochemistry, genetics and molecular biology

New anti-malarial phenylpropanoid conjugated iridoids from Morinda morindoides

Bioorganic and Medicinal Chemistry Letters, Volume 20, No. 5, Year 2010

A new phenylpropanoid conjugated iridoid together with four known congeners was isolated from Morinda morindoides, used for the therapy of malaria traditionally in some African countries, as anti-malarial principles through bioassay-guided separation. Furthermore, their absolute stereostructures were unambiguously established by a combination of modified Mosher's method and chemical correlation. © 2010 Elsevier Ltd. All rights reserved.

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Citations: 7
Authors: 7
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Infectious Diseases