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Publication Details
AFRICAN RESEARCH NEXUS
SHINING A SPOTLIGHT ON AFRICAN RESEARCH
Assessment of changes in risk behaviors during 3 years of posttrial follow-up of male circumcision trial participants uncircumcised at trial closure in Rakai, Uganda
American Journal of Epidemiology, Volume 176, No. 10, Year 2012
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Description
Risk compensation associated with male circumcision has been a concern for male circumcision scale-up programs. Using posttrial data collected during 2007-2011 on 2,137 male circumcision trial participants who were uncircumcised at trial closure in Rakai, Uganda, the authors evaluated their sexual behavioral changes during approximately 3 years follow-up after trial closure. Eighty-one percent of the men self-selected for male circumcision during the period, and their sociodemographic and risk profiles were comparable to those of men remaining uncircumcised. Linear models for marginal probabilities of repeated outcomes estimate that 3.3 (P < 0.0001) of the male circumcision acceptors reduced their engagement in nonmarital relations, whereas there was no significant change among men remaining uncircumcised. Significant decreases in condom use occurred in both male circumcision acceptors (-9.2 with all partners and -7.0 with nonmarital partners) and nonacceptors (-12.4 and -13.5, respectively), and these were predominantly among younger men. However, the magnitudes of decrease in condom use were not significantly different between the 2 groups. Additionally, significant decreases in sex-related alcohol consumption were observed in both groups (-7.8 in male circumcision acceptors and -6.1 in nonacceptors), mainly among older men. In summary, there was no evidence of risk compensation associated with male circumcision among this cohort of men during 3 years of posttrial follow-up. © The Author 2012.
Authors & Co-Authors
Kong, Xiangrong
United States, Baltimore
Johns Hopkins Bloomberg School of Public Health
Kigozi, Godfrey G.
United States, Baltimore
Johns Hopkins Bloomberg School of Public Health
Nalugoda, Fred Kakaire
United States, Baltimore
Johns Hopkins Bloomberg School of Public Health
Musoke, Richard M.
United States, Baltimore
Johns Hopkins Bloomberg School of Public Health
Kagaayi, Joseph
United States, Baltimore
Johns Hopkins Bloomberg School of Public Health
Latkin, Carl A.
United States, Baltimore
Johns Hopkins Bloomberg School of Public Health
Ssekubugu, Robert
United States, Baltimore
Johns Hopkins Bloomberg School of Public Health
Lutalo, Tom
United States, Baltimore
Johns Hopkins Bloomberg School of Public Health
Nantume, Betty S.
United States, Baltimore
Johns Hopkins Bloomberg School of Public Health
Boaz, Iga
United States, Baltimore
Johns Hopkins Bloomberg School of Public Health
Wawer, Maria J.
United States, Baltimore
Johns Hopkins Bloomberg School of Public Health
Serwadda, David Musoke
United States, Baltimore
Johns Hopkins Bloomberg School of Public Health
Gray, Ronald H.
United States, Baltimore
Johns Hopkins Bloomberg School of Public Health
Statistics
Citations: 63
Authors: 13
Affiliations: 1
Identifiers
Doi:
10.1093/aje/kws179
ISSN:
14766256
Research Areas
Sexual And Reproductive Health
Substance Abuse
Study Design
Cohort Study
Study Locations
Uganda
Participants Gender
Male