Exploring early steps in biofilm formation: Set-up of an experimental system for molecular studies
BMC Microbiology, Volume 14, No. 1, Article 253, Year 2014
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Background: Bacterial biofilms are predominant in natural ecosystems and constitute a public health threat because of their outstanding resistance to antibacterial treatments and especially to antibiotics. To date, several systems have been developed to grow bacterial biofilms in order to study their phenotypes and the physiology of sessile cells. Although relevant, such systems permit analysis of various aspects of the biofilm state but often after several hours of bacterial growth.