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Publication Details
AFRICAN RESEARCH NEXUS
SHINING A SPOTLIGHT ON AFRICAN RESEARCH
immunology and microbiology
Kala-azar: A comparative study of parasitological methods and the direct agglutination test in diagnosis
Transactions of the Royal Society of Tropical Medicine and Hygiene, Volume 86, No. 5, Year 1992
Notification
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Description
In a comparative study 88 patients were diagnosed as suffering from kala-azar (visceral leishmaniasis) using 3 parasitological methods simultaneously. Splenomegaly was absent in 4 cases. In 84 patients with splenomegaly, splenic aspiration appeared to be the most sensitive method (96·4%), followed by bone marrow aspiration (70·2%) and lymph node aspiration (58·3%). There was no relation between titres in the direct agglutination test and parasite load as determined by the number of parasitological methods which were positive or parasite density in splenic aspirates. Splenic aspiration and bone marrow aspiration were compared as an assessment of cure in kala-azar. In 6 (13%) of 46 patients tested, parasites were found, all by splenic aspiration. Bone marrow showed parasites in one of these. The literature with regard to parasitological investigations before and after treatment is reviewed. © 1992 Oxford university press.
Authors & Co-Authors
Zijlstra, D. E.
Sudan, Khartoum
Medical Research Council
Netherlands
M裥cins Sans Fronti籥s
Siddig Ali, M.
Sudan, Khartoum
Medical Research Council
el-Hassan, Ahmed Mohamed A.
Sudan, Khartoum
Medical Research Council
El-Toum, Isam A.
Sudan, Khartoum
Medical Research Council
Satti, Maria H.
Sudan, Khartoum
Medical Research Council
Ghalib, Hashim Warsama
Sudan, Khartoum
Medical Research Council
Kager, Petrus A.
Netherlands, Amsterdam
Amsterdam Umc - University of Amsterdam
Statistics
Citations: 220
Authors: 7
Affiliations: 3
Identifiers
Doi:
10.1016/0035-9203(92)90086-R
ISSN:
00359203
e-ISSN:
18783503