Skip to content
Home
About Us
Resources
Profiles Metrics
Authors Directory
Institutions Directory
Top Authors
Top Institutions
Top Sponsors
AI Digest
Contact Us
Menu
Home
About Us
Resources
Profiles Metrics
Authors Directory
Institutions Directory
Top Authors
Top Institutions
Top Sponsors
AI Digest
Contact Us
Home
About Us
Resources
Profiles Metrics
Authors Directory
Institutions Directory
Top Authors
Top Institutions
Top Sponsors
AI Digest
Contact Us
Menu
Home
About Us
Resources
Profiles Metrics
Authors Directory
Institutions Directory
Top Authors
Top Institutions
Top Sponsors
AI Digest
Contact Us
Publication Details
AFRICAN RESEARCH NEXUS
SHINING A SPOTLIGHT ON AFRICAN RESEARCH
agricultural and biological sciences
Worldwide patterns of genetic differentiation imply multiple 'domestications' of Aedes aegypti, a major vector of human diseases
Proceedings of the Royal Society B: Biological Sciences, Volume 278, No. 1717, Year 2011
Notification
URL copied to clipboard!
Description
Understanding the processes bywhich species colonize and adapt tohuman habitats is particularly important in the case of disease-vectoring arthropods. The mosquito species Aedes aegypti, a major vector of dengue and yellow fever viruses, probably originated as a wild, zoophilic species in sub-Saharan Africa, where some populations still breed in tree holes in forested habitats.Many populations of the species, however, have evolved to thrive in human habitats and to bite humans. This includes some populationswithin Africa aswell as almost all those outsideAfrica. It is not clearwhether all domestic populations are genetically related and represent a single 'domestication' event, orwhether associationwith human habitats has developed multiple times independently within the species.To test the hypotheses above,we screened 24worldwide population samples of Ae. aegypti at 12 polymorphic microsatellite loci. We identified two distinct genetic clusters: one included all domestic populations outside of Africa and the other included both domestic and forest populations within Africa. This suggests that human association in Africa occurred independently from that in domestic populations across the rest of the world. Additionally, measures of genetic diversity support Ae. aegypti in Africa as the ancestral form of the species. Individuals from domestic populations outside Africa can reliably be assigned back to their population of origin, which will help determine the origins of new introductions of Ae. aegypti. © 2011 The Royal Society.
Authors & Co-Authors
Brown, J. E.
Unknown Affiliation
McBride, Carolyn S.
Unknown Affiliation
Johnson, Petrina
Unknown Affiliation
Ritchie, Scott
Unknown Affiliation
Paupy, Christophe
Unknown Affiliation
Bossin, Hervé Christophe
Unknown Affiliation
Lutomiah, Joel J.L.
Unknown Affiliation
Fernandez-Salas, Ildefonso
Unknown Affiliation
Ponlawat, Alongkot
Unknown Affiliation
Cornel, Anthony John
Unknown Affiliation
Black IV, William C.
Unknown Affiliation
Gorrochotegui-Escalante, Norma
Unknown Affiliation
Urdaneta-Marquez, Ludmel
Unknown Affiliation
Sylla, Massamba
Unknown Affiliation
Slotman, Michel Andre
Unknown Affiliation
Murray, Kristy O.
Unknown Affiliation
Walker, Christopher
Unknown Affiliation
Powell, Jeffrey Robert
Unknown Affiliation
Statistics
Citations: 245
Authors: 18
Affiliations: 13
Identifiers
Doi:
10.1098/rspb.2010.2469
ISSN:
09628452
Research Areas
Genetics And Genomics
Infectious Diseases
Study Design
Cross Sectional Study