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Publication Details
AFRICAN RESEARCH NEXUS
SHINING A SPOTLIGHT ON AFRICAN RESEARCH
immunology and microbiology
Infectious etiologies of acute febrile illness among patients seeking health care in South-Central Cambodia
American Journal of Tropical Medicine and Hygiene, Volume 86, No. 2, Year 2012
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Description
The agents of human febrile illness can vary by region and country suggesting that diagnosis, treatment, and control programs need to be based on a methodical evaluation of area-specific etiologies. From December 2006 to December 2009, 9,997 individuals presenting with acute febrile illness at nine health care clinics in south-central Cambodia were enrolled in a study to elucidate the etiologies. Upon enrollment, respiratory specimens, whole blood, and serum were collected. Testing was performed for viral, bacterial, and parasitic pathogens. Etiologies were identified in 38.0% of patients. Influenza was the most frequent pathogen, followed by dengue, malaria, and bacterial pathogens isolated from blood culture. In addition, 3.5% of enrolled patients were infected with more than one pathogen. Our data provide the first systematic assessment of the etiologies of acute febrile illness in south-central Cambodia. Data from syndromic-based surveillance studies can help guide public health responses in developing nations. Copyright © 2012 by The American Society of Tropical Medicine and Hygiene.
Authors & Co-Authors
Kasper, Matthew R.
Peru, Lima
Naval Medical Research Unit No. 6
Blair, Patrick J.
United States, San Diego
Naval Medical Center San Diego
Touch, Sok
Unknown Affiliation
Yasuda, Chadwick Y.
Unknown Affiliation
Williams, Maya
Peru, Lima
Naval Medical Research Unit No. 6
Richards, Allen L.
United States, Silver Spring
Naval Medical Research Center
Burgess, Timothy H.
United States, Rockville
National Cancer Institute Nci
Wierzba, Thomas F.
South Korea, Seoul
International Vaccine Institute, Seoul
Putnam, Shannon D.
United States, San Diego
Naval Medical Center San Diego
Statistics
Citations: 86
Authors: 9
Affiliations: 6
Identifiers
Doi:
10.4269/ajtmh.2012.11-0409
ISSN:
00029637
Research Areas
Health System And Policy
Infectious Diseases