Wide-field fundus autofluorescence corresponds to visual fields in chorioretinitis patients

Background and objectives: Detection of peripheral fundus autofluorescence (FAF) using conventional scanning laser ophthalmoscopes (SLOs) is difficult and requires pupil dilation. Here we evaluated the diagnostic properties of wide-field FAF detected by a two-laser wave-length wide-field SLO in uveitis patients. Study design/materials and methods: Observational case series of four patients suffering from different types of posterior uveitis/chorioretinitis. Wide-field FAF images were compared to visual fields. Panretinal FAF was detected by a newly developed SLO, which allows FAF imaging of up to 200° of the retina in one scan without the need for pupil dilation. Visual fields were obtained by Goldmann manual perimetry. Results: Findings from wide-field FAF imaging showed correspondence to visual field defects in all cases. Conclusion: Wide-field FAF allowed the detection of visual field defect-related alterations of the retinal pigment epithelium in all four uveitis cases. © 2011 Seidensticker et al, publisher and licensee Dove Medical Press Ltd.