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Publication Details
AFRICAN RESEARCH NEXUS
SHINING A SPOTLIGHT ON AFRICAN RESEARCH
medicine
Contemporary National Trends and Outcomes of Pulmonary Embolism in the United States
American Journal of Cardiology, Volume 176, Year 2022
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Description
Contemporary data on the national trends in pulmonary embolism (PE) admissions and outcomes are scarce. We aimed to analyze trends in mortality and different treatment methods in acute PE. We queried the Nationwide Readmissions Database (2016 to 2019) to identify hospitalizations with acute PE using the International Classification of Diseases, Tenth Revision, Clinical Modification codes. We described the national trends in admissions, in-hospital mortality, readmissions, and different treatment methods in acute PE. We identified 1,427,491 hospitalizations with acute PE, 2.4% of them (n = 34,446) were admissions with high-risk PE. The rate of in-hospital mortality in all PE hospitalizations was 6.5%, and it remained unchanged throughout the study period. However, the rate of in-hospital mortality in high-risk PE decreased from 48.1% in the first quarter of 2016 to 38.9% in the last quarter of 2019 (p-trend <0.001). The rate of urgent 30-day readmission was 15.2% in all PE admissions and 19.1% in high-risk PE admissions. In all PE admissions, catheter-directed interventions (CDI) were used more often (2.5%) than systemic thrombolysis (ST) (2.1%). However, in admissions with high-risk PE, ST remained the most frequently used method (ST vs CDI: 11.3% vs 6.6%). In conclusion, this study showed that the rate of in-hospital mortality in high-risk PE decreased from 2016 to 2019. ST was the most frequently used method for achieving pulmonary reperfusion in high-risk PE, whereas CDI was the most frequently used method in the entire PE cohort. In-hospital death and urgent readmissions rates remain significantly high in patients with high-risk PE. © 2022 Elsevier Inc.
Authors & Co-Authors
Sedhom, Ramy
United States, Philadelphia
Albert Einstein Medical Center
Megaly, Michael S.
United States, Detroit
Henry Ford Hospital
Elbadawi, Ayman
United States, Houston
Baylor College of Medicine
Elgendy, Islam Y.
Qatar, Doha
Weill Cornell Medicine-qatar
Omer, Mohamed A.
United States, Rochester
Mayo Clinic
Banerjee, Subhash
United States, Dallas
Ut Southwestern Medical Center
Jaber, Wissam A.
United States, Atlanta
Emory University School of Medicine
Shishehbor, Mehdi H.
United States, Cleveland
University Hospitals Case Medical Center
Statistics
Citations: 14
Authors: 8
Affiliations: 10
Identifiers
Doi:
10.1016/j.amjcard.2022.03.060
ISSN:
00029149
Research Areas
Health System And Policy
Study Design
Cohort Study