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Publication Details
AFRICAN RESEARCH NEXUS
SHINING A SPOTLIGHT ON AFRICAN RESEARCH
agricultural and biological sciences
Integrated rapid mapping of onchocerciasis and loiasis in the Democratic Republic of Congo: Impact on control strategies
Acta Tropica, Volume 120, No. SUPPL. 1, Year 2011
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Description
Background: Onchocerciasis can be effectively controlled by annual mass treatment with ivermectin in endemic communities. However, in communities that are endemic for loiasis there may be significant risk of severe adverse reactions after ivermectin treatment. Planning of control requires therefore mapping of these two infections using rapid assessment tools developed for each disease. These tools were initially implemented independently till the feasibility of combining them was demonstrated. This paper reports the results of integrated mapping in four epidemiological zones in the Democratic Republic of Congo and its implications on operational decision-making on ivermectin treatment. Methods: Rapid assessment surveys were conducted between 2004 and 2005 using both rapid epidemiological mapping of onchocerciasis (REMO) and rapid assessment procedure for loiasis (RAPLOA). The survey results were subjected to a spatial analysis in order to generate for each of the two diseases maps of the estimated prevalence of infection throughout the four zones. Results: Surveys were undertaken in 788 villages where 25,754 males were examined for palpable onchocercal nodules and 62,407 people were interviewed for history of eye worm. The results showed major differences in the geographic distribution of the two diseases. Loiasis was highly endemic in some areas, where special precautions were required, but not in others where routine ivermectin treatment could proceed. Conclusion: Integrated rapid mapping of onchocerciasis and loiasis reduces both time and cost of surveys and greatly facilitates operational decision-making on ivermectin treatment in areas where loiasis might be co-endemic. © 2010 Elsevier B.V.
Authors & Co-Authors
Tekle, Afework Hailemariam
Unknown Affiliation
Zouré, Honorat Gustave Marie
Unknown Affiliation
Wanji, Samuel
Cameroon
Research Foundation in Tropical Diseases and Environment
Leak, Stephen
Unknown Affiliation
Noma, Mounkaïla M.
Unknown Affiliation
Remme, Jan Hans F.
Unknown Affiliation
Amazigo, Uche V.
Unknown Affiliation
Statistics
Citations: 31
Authors: 7
Affiliations: 2
Identifiers
Doi:
10.1016/j.actatropica.2010.05.008
ISSN:
0001706X
e-ISSN:
18736254
Research Areas
Health System And Policy
Infectious Diseases
Study Design
Cross Sectional Study
Study Approach
Quantitative
Study Locations
Congo