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Publication Details
AFRICAN RESEARCH NEXUS
SHINING A SPOTLIGHT ON AFRICAN RESEARCH
medicine
Alcohol consumption and non-communicable diseases: Epidemiology and policy implications
Addiction, Volume 106, No. 10, Year 2011
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Description
Aims This paper summarizes the relationships between different patterns of alcohol consumption and various on non-communicable disease (NCD) outcomes and estimates the percentage of NCD burden that is attributable to alcohol. Methods A narrative review, based on published meta-analyses of alcohol consumption-disease relations, together with an examination of the Comparative Risk Assessment estimates applied to the latest available revision of Global Burden of Disease study. Results Alcohol is causally linked (to varying degrees) to eight different cancers, with the risk increasing with the volume consumed. Similarly, alcohol use is related detrimentally to many cardiovascular outcomes, including hypertension, haemorrhagic stroke and atrial fibrillation. For other cardiovascular outcomes the relationship is more complex. Alcohol is furthermore linked to various forms of liver disease (particularly with fatty liver, alcoholic hepatitis and cirrhosis) and pancreatitis. For diabetes the relationship is also complex. Conservatively, of the global NCD-related burden of deaths, net years of life lost (YLL) and net disability adjusted life years (DALYs), 3.4%, 5.0% and 2.4%, respectively, can be attributed to alcohol consumption, with the burden being particularly high for cancer and liver cirrhosis. This burden is especially pronounced in countries of the former Soviet Union. Conclusions There is a strong link between alcohol and non-communicable diseases, particularly cancer, cardiovascular disease, liver disease, pancreatitis and diabetes, and these findings support calls by the World Health Organization to implement evidence-based strategies to reduce harmful use of alcohol. © 2011 The Authors, Addiction © 2011 Society for the Study of Addiction.
Authors & Co-Authors
Parry, Charles D.H.
South Africa, Tygerberg
South African Medical Research Council
South Africa, Stellenbosch
Stellenbosch University
Patra, Jayadeep
Canada, Toronto
Centre for Addiction and Mental Health
Canada, Toronto
University of Toronto
Rehm, Jurgen T.
Canada, Toronto
Centre for Addiction and Mental Health
Canada, Toronto
University of Toronto
Germany, Dresden
Technische Universität Dresden
Statistics
Citations: 263
Authors: 3
Affiliations: 5
Identifiers
Doi:
10.1111/j.1360-0443.2011.03605.x
e-ISSN:
13600443
Research Areas
Cancer
Disability
Health System And Policy
Infectious Diseases
Noncommunicable Diseases
Substance Abuse
Study Design
Narrative Study
Study Approach
Qualitative