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Publication Details
AFRICAN RESEARCH NEXUS
SHINING A SPOTLIGHT ON AFRICAN RESEARCH
medicine
Developing WHO guidelines with pragmatic, structured, evidence-based processes: A case study
Global Public Health, Volume 5, No. 4, Year 2010
Notification
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Description
Many guidelines, including those produced by the World Health Organisation (WHO), have failed to adhere to rigorous methodological standards. Operational examples of guideline development processes may provide important lessons learned to improve the rigour and quality of future guidelines. To this end, this paper describes the process of developing WHO guidelines on prevention and care interventions for adults and adolescents living with HIV. Using a pragmatic, structured, evidence-based approach, we created an organising committee, identified topics, conducted systematic reviews, identified experts and distributed evidence summaries. Subsequently, 55 global HIV experts drafted and anonymously submitted guideline statements at the beginning of a conference. During the conference, participants voted on statements using scales evaluating appropriateness of the statements, strength of recommendation and level of evidence. After review of voting results, open discussion, re-voting and refinement of statements, a draft version of the guidelines was completed. A post-conference writing team refined the guidelines based on pre-determined guideline writing principles and incorporated external comments into a final document. Successes and challenges of the guideline development process were identified and are used to highlight current issues and debates in developing guidelines with a focus on implications for future guideline development at WHO. © 2010 Taylor & Francis.
Authors & Co-Authors
Chang, Larry William
United States, San Francisco
University of California, San Francisco
United States, Baltimore
Johns Hopkins Medical Institutions
Kennedy, Caitlin E.
United States, Baltimore
Johns Hopkins Bloomberg School of Public Health
Kennedy, Gail E.
United States, San Francisco
University of California, San Francisco
Lindegren, Mary Lou
United States, Atlanta
National Center for Hiv, Viral Hepatitis, Std, and tb Prevention
Marston, Barbara J.
United States, Atlanta
National Center for Hiv, Viral Hepatitis, Std, and tb Prevention
Kaplan, Jonathan E.
United States, Atlanta
National Center for Hiv, Viral Hepatitis, Std, and tb Prevention
Sweat, Michael D.
United States, Charleston
Musc College of Medicine
Bunnell, Rebecca E.
Kenya, Nairobi
Gap
O’Reilly, Kevin R.
Switzerland, Geneva
Unaids
Rutherford, George Williams
United States, San Francisco
University of California, San Francisco
Mermin, Jonathan H.
Kenya, Nairobi
Coordinating Office of Global Health
Statistics
Citations: 11
Authors: 11
Affiliations: 8
Identifiers
Doi:
10.1080/17441690903473253
ISSN:
17441692
e-ISSN:
17441706
Research Areas
Infectious Diseases
Study Design
Case Study
Study Approach
Qualitative