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Publication Details
AFRICAN RESEARCH NEXUS
SHINING A SPOTLIGHT ON AFRICAN RESEARCH
Isolated Kaposi Sarcoma in two HIV negative patients
Journal of Dermatological Case Reports, Volume 5, No. 2, Year 2011
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Description
Background: Kaposi sarcoma (KS) is a neoplasm of the endothelial cells. It often manifests with multiple vascular nodules on the skin and other organs. It is a systemic, malignant and multifactorial disease and has a variable course. There are four types: classic, endemic, iatrogenic and HIV-associated. The primary presentation on the penis and face is uncommon and is mainly observed in HIV-positive patients. Multiple treatment modalities are used including surgery, cryotherapy, electrosurgery, laser and radiation therapy. Main observation: The authors present two cases of isolated Kaposi sarcoma in HIV negative, human herpes virus 8 (HHV-8) positive non immunocompromised patients. One case with facial KS and the other one with penile KS. Both were treated surgically with no recurrence in the following 6 months of the follow up period. Conclusions: Kaposi sarcoma is rare in HIV negative patients and is associated with HHV-8 infection. Lesions are usually solitary and can be treated surgically. It should be included in the differential diagnoses of penile and facial lesions that are clinically suspecious and resistent to therapy. © Journal of Dermatological Case Reports.
Authors & Co-Authors
Seleit, Iman Abdel Fattah
Egypt, Shibin el Kom
Menoufia University Faculty of Medicine
Attia, Abdalla Mohamed
Egypt, Shibin el Kom
Menoufia University Faculty of Medicine
Maraee, Alaa Hassan
Egypt, Shibin el Kom
Menoufia University Faculty of Medicine
Samaka, Rehab Monir Onir
Egypt, Shibin el Kom
Menoufia University Faculty of Medicine
Bakry, Ola Ahmed
Egypt, Shibin el Kom
Menoufia University Faculty of Medicine
Eid, Emad
Egypt, Shibin el Kom
Menoufia University Faculty of Medicine
Statistics
Citations: 27
Authors: 6
Affiliations: 1
Identifiers
Doi:
10.3315/jdcr.2011.1067
e-ISSN:
18987249
Research Areas
Cancer
Health System And Policy
Infectious Diseases