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Publication Details
AFRICAN RESEARCH NEXUS
SHINING A SPOTLIGHT ON AFRICAN RESEARCH
medicine
Prevalence of HBeAg, anti-HBe serological markers and HBV-DNA in asymptomatic carriers in Ethiopia
European Journal of Epidemiology, Volume 5, No. 4, Year 1989
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Description
Data on the distribution of HBV-DNA and other serological markers of hepatitis B virus infection in a population of asymptomatic carriers in Ethiopia are reported. As compared to data from other countries of similar or lower levels of endemicity, it has been found that HBV-DNA prevalence and its correlation with HBeAg/anti-HBe status is similar to that of northern Europe. HBV-DNA is present in 84% of HBe Ag-positive sera but in only 4% of anti-HBe-positive sera, where the lowest concentration of DNA (less than 5 pgr/20 μl) was found. The trend of increasing prevalence of serological markers with age seems to indicate a considerable horizontal transmission still present in this age range (18-30). In keeping with data of other authors a 3% of HBV-DNA positivity in anti HBc only positive sera was found. No regional or ethnical differences of HBV-DNA positive sera across the country were observed. There is also no evidence of any correlation between HBV-DNA prevalence and HBsAg subtypes ad and ay. © 1989 Kluwer Academic Publishers.
Authors & Co-Authors
Rapicetta, Mariella
Italy, Rome
Istituto Superiore Di Sanita
Hailù, K.
Ethiopia, Addis Ababa
Military Hospital
Morace, G.
Italy, Rome
Istituto Superiore Di Sanita
Bisanti, Luigi
Italy, Rome
Istituto Superiore Di Sanita
Di Rienzo, A.
Italy, Rome
Istituto Superiore Di Sanita
Ciccaglione, A. R.
Italy, Rome
Istituto Superiore Di Sanita
Bekura, D.
Ethiopia, Addis Ababa
Military Hospital
Pasquini, Paolo
Italy, Rome
Istituto Superiore Di Sanita
Rossi, G. B.
Italy, Rome
Istituto Superiore Di Sanita
Statistics
Citations: 9
Authors: 9
Affiliations: 2
Identifiers
Doi:
10.1007/BF00140145
e-ISSN:
15737284
Research Areas
Genetics And Genomics
Infectious Diseases
Study Design
Cross Sectional Study
Study Locations
Ethiopia