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Publication Details
AFRICAN RESEARCH NEXUS
SHINING A SPOTLIGHT ON AFRICAN RESEARCH
immunology and microbiology
Adherence to 7-day primaquine treatment for the radical cure of P. vivax in the Peruvian Amazon
American Journal of Tropical Medicine and Hygiene, Volume 82, No. 6, Year 2010
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Description
Despite being free of charge, treatment adherence to 7-day primaquine for the radical cure of Plasmodium vivax was estimated at 62.2% among patients along the Iquitos-Nauta road in the Peruvian Amazon. The principal reason for non-adherence was the perceived adverse effects related to local humoral illness conceptions that hold that malaria produces a hot state of body, which is further aggravated by the characteristically hot medical treatment. Notably, patients were willing to adhere to the first 3 days of treatment during which symptoms are most apparent and include the characteristic chills. Nevertheless, as symptoms abate, the perceived aggravating characteristics of the medication outweigh the perceived advantages of treatment adherence. Improving community awareness about the role of primaquine to prevent further malaria transmission and fostering a realistic system of direct observed treatment intake, organized at community level, can be expected to improve adherence to the radical cure of P. vivax in this area. Copyright © 2010 by The American Society of Tropical Medicine and Hygiene.
Authors & Co-Authors
Peeters-Grietens, Koen
Belgium, Antwerpen
Prins Leopold Instituut Voor Tropische Geneeskunde
Soto-Calle, Verónica E.
Peru, Lima
Universidad Peruana Cayetano Heredia
Erhart, Annette
Belgium, Antwerpen
Prins Leopold Instituut Voor Tropische Geneeskunde
Ribera, Joan Muela
Belgium, Tessenderlo
Pass International
Toomer, Elizabeth
Belgium, Tessenderlo
Pass International
Tenorio, Alex
Peru, Lima
Universidad Peruana Cayetano Heredia
Rodrıguez-Ferrucci, Hugo
Unknown Affiliation
Llanos-Cuentas, E. Alejandro
Peru, Lima
Universidad Peruana Cayetano Heredia
D'Alessandro, Umberto
Belgium, Antwerpen
Prins Leopold Instituut Voor Tropische Geneeskunde
Gamboa Vilela, Dionicia V.
Peru, Lima
Universidad Peruana Cayetano Heredia
Statistics
Citations: 70
Authors: 10
Affiliations: 3
Identifiers
Doi:
10.4269/ajtmh.2010.09-0521
ISSN:
00029637
Research Areas
Health System And Policy
Infectious Diseases