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Publication Details
AFRICAN RESEARCH NEXUS
SHINING A SPOTLIGHT ON AFRICAN RESEARCH
biochemistry, genetics and molecular biology
Population genetics of the malmö polymorphism of coagulation factor IX
Human Heredity, Volume 41, No. 6, Year 1991
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Description
The distribution of 1.198 Malmö alleles was examined in 822 men from 16 indigenous populations and 188 women from 7 of the ethnic groups. Subjects were from several European countries, the Mediterranean, East Asia, and the USA (Anglo- and African-Americans). The frequencies of the rarer (Malmö B) allele were approximately equal across Europe, the highest frequencies (0.36) being in the French and Anglo-Americans; no population was observed with clearly the highest frequency. They diminished slightly at moderate distances from Europe (Tunisia. Ethiopia) and greatly at longer distances (East Asia and West Africa). In Orientals, the frequencies ranged from 0.07 (East Indians) to 0.03 (the Chinese) and from 0.0 to 0.15 in African-Americans. Assuming selective neutrality, the data are consistent with the European origin of the ‘B’ allele when the population was small and outward spread. © 1991 S. Karger AG, Basel.
Authors & Co-Authors
Wallmark, Anders
Sweden, Lund
Lunds Universitet
Kunkel, Glenna
United States, Chapel Hill
The University of North Carolina at Chapel Hill
Mouhli, Hassan
Tunisia, Tunis
Université de Tunis
Bosco, John
Malaysia, Kuala Lumpur
University of Malaysia
Ljung, Rolf C.R.
Sweden, Lund
Lunds Universitet
Nilsson, Inga Marie
Sweden, Lund
Lunds Universitet
Graham, John B.
United States, Chapel Hill
The University of North Carolina at Chapel Hill
Statistics
Citations: 12
Authors: 7
Affiliations: 4
Identifiers
Doi:
10.1159/000154032
ISSN:
00015652
e-ISSN:
14230062
Research Areas
Genetics And Genomics
Study Design
Cross Sectional Study
Study Locations
Multi-countries
Ethiopia
Tunisia
Participants Gender
Male
Female