Skip to content
Home
About Us
Resources
Profiles Metrics
Authors Directory
Institutions Directory
Top Authors
Top Institutions
Top Sponsors
AI Digest
Contact Us
Menu
Home
About Us
Resources
Profiles Metrics
Authors Directory
Institutions Directory
Top Authors
Top Institutions
Top Sponsors
AI Digest
Contact Us
Home
About Us
Resources
Profiles Metrics
Authors Directory
Institutions Directory
Top Authors
Top Institutions
Top Sponsors
AI Digest
Contact Us
Menu
Home
About Us
Resources
Profiles Metrics
Authors Directory
Institutions Directory
Top Authors
Top Institutions
Top Sponsors
AI Digest
Contact Us
Publication Details
AFRICAN RESEARCH NEXUS
SHINING A SPOTLIGHT ON AFRICAN RESEARCH
medicine
Designing Programs for Eliminating Canine Rabies from Islands: Bali, Indonesia as a Case Study
PLoS Neglected Tropical Diseases, Volume 7, No. 8, Article e2372, Year 2013
Notification
URL copied to clipboard!
Description
Background:Canine rabies is one of the most important and feared zoonotic diseases in the world. In some regions rabies elimination is being successfully coordinated, whereas in others rabies is endemic and continues to spread to uninfected areas. As epidemics emerge, both accepted and contentious control methods are used, as questions remain over the most effective strategy to eliminate rabies. The Indonesian island of Bali was rabies-free until 2008 when an epidemic in domestic dogs began, resulting in the deaths of over 100 people. Here we analyze data from the epidemic and compare the effectiveness of control methods at eliminating rabies.Methodology/Principal Findings:Using data from Bali, we estimated the basic reproductive number, R0, of rabies in dogs, to be ∼1·2, almost identical to that obtained in ten-fold less dense dog populations and suggesting rabies will not be effectively controlled by reducing dog density. We then developed a model to compare options for mass dog vaccination. Comprehensive high coverage was the single most important factor for achieving elimination, with omission of even small areas (<0.5% of the dog population) jeopardizing success. Parameterizing the model with data from the 2010 and 2011 vaccination campaigns, we show that a comprehensive high coverage campaign in 2012 would likely result in elimination, saving ∼550 human lives and ∼$15 million in prophylaxis costs over the next ten years.Conclusions/Significance:The elimination of rabies from Bali will not be achieved through achievable reductions in dog density. To ensure elimination, concerted high coverage, repeated, mass dog vaccination campaigns are necessary and the cooperation of all regions of the island is critical. Momentum is building towards development of a strategy for the global elimination of canine rabies, and this study offers valuable new insights about the dynamics and control of this disease, with immediate practical relevance. © 2013 Townsend et al.
Available Materials
https://efashare.b-cdn.net/share/pmc/articles/PMC3749988/bin/pntd.0002372.s001.docx
https://efashare.b-cdn.net/share/pmc/articles/PMC3749988/bin/pntd.0002372.s002.avi
https://efashare.b-cdn.net/share/pmc/articles/PMC3749988/bin/pntd.0002372.s003.avi
https://efashare.b-cdn.net/share/pmc/articles/PMC3749988/bin/pntd.0002372.s004.avi
https://efashare.b-cdn.net/share/pmc/articles/PMC3749988/bin/pntd.0002372.s005.avi
https://efashare.b-cdn.net/share/pmc/articles/PMC3749988/bin/pntd.0002372.s006.avi
https://efashare.b-cdn.net/share/pmc/articles/PMC3749988/bin/pntd.0002372.s007.avi
Authors & Co-Authors
Townsend, Sunny E.
United Kingdom, Glasgow
University of Glasgow
Sumantra, I. Putu
Indonesia
Bali Province Livestock Services
Pudjiatmoko,
Indonesia, Jakarta
Ministry of Agriculture, Indonesia
Bagus, Gusti Ngurah
Indonesia
Bali Animal Welfare Association
Brum, Eric
Indonesia, Jakarta
Food and Agriculture Organization of the United Nations, Indonesia
Cleaveland, Sarah C.
United Kingdom, Glasgow
University of Glasgow
Crafter, Sally
Indonesia, Jakarta
Food and Agriculture Organization of the United Nations, Indonesia
Dewi, Ayu P.M.
Indonesia, Jakarta
Food and Agriculture Organization of the United Nations, Indonesia
Dharma, Dewa Made Ngurah
Indonesia
Disease Investigation Center Denpasar
Dushoff, Jonathan G.
Canada, Hamilton
Mcmaster University
Girardi, Janice
Indonesia
Bali Animal Welfare Association
Gunata, I. Ketut
Indonesia
Badung District Livestock Services
Hiby, Elly F.
United Kingdom, London
World Animal Protection uk
Kalalo, Corlevin
Indonesia
Bali Animal Welfare Association
Knobel, Darryn L.
South Africa, Pretoria
University of Pretoria
Mardiana, I. Wayan
Indonesia
Bali Province Livestock Services
Putra, Anak Agung Gde
Indonesia
Disease Investigation Center Denpasar
Schoonman, Luuk B.
Indonesia, Jakarta
Food and Agriculture Organization of the United Nations, Indonesia
Scott-Orr, Helen
Australia, Sydney
The University of Sydney
Shand, Mike Clarke
United Kingdom, Glasgow
University of Glasgow
Sukanadi, I. Wayan
Indonesia
Bali Province Livestock Services
Suseno, Pebi Purwo
Indonesia, Jakarta
Ministry of Agriculture, Indonesia
Haydon, Daniel Thomas
United Kingdom, Glasgow
University of Glasgow
Hampson, Katie
United Kingdom, Glasgow
University of Glasgow
Statistics
Citations: 138
Authors: 24
Affiliations: 11
Identifiers
Doi:
10.1371/journal.pntd.0002372
ISSN:
19352727
e-ISSN:
19352735
Research Areas
Health System And Policy
Infectious Diseases
Sexual And Reproductive Health
Study Design
Cross Sectional Study
Case Study
Study Approach
Qualitative