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Publication Details
AFRICAN RESEARCH NEXUS
SHINING A SPOTLIGHT ON AFRICAN RESEARCH
medicine
The diagnostic performance of artificial intelligence algorithms for identifying M2 segment middle cerebral artery occlusions: A systematic review and meta-analysis
Journal of Neuroradiology, Volume 50, No. 4, Year 2023
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Description
Background: Artificial intelligence (AI)-based algorithms have been developed to facilitate rapid and accurate computed tomography angiography (CTA) assessment in proximal large vessel occlusion (LVO) acute ischemic stroke, including internal carotid artery and M1 occlusions. In clinical practice, however, the detection of medium vessel occlusion (MeVO) represents an ongoing diagnostic challenge in which the added value of AI remains unclear. Purpose: To assess the diagnostic performance of AI platforms for detecting M2 occlusions. Methods: Studies that report the diagnostic performance of AI-based detection of M2 occlusions were screened, and sensitivity and specificity data were extracted using the semi-automated AutoLit software (Nested Knowledge, MN) platform. STATA (version 16 IC; Stata Corporation, College Station, Texas, USA) was used to conduct all analyses. Results: Eight studies with a low risk of bias and significant heterogeneity were included in the quantitative and qualitative synthesis. The pooled estimates of sensitivity and specificity of AI platforms for M2 occlusion detection were 64% (95% CI, 53 to 74%) and 97% (95% CI, 84 to 100%), respectively. The area under the curve (AUC) in the SROC curve was 0.79 (95% CI, 0.74 to 0.83). Conclusion: The current performance of the AI-based algorithm makes it more suitable as an adjunctive confirmatory tool rather than as an independent one for M2 occlusions. With the rapid development of such algorithms, it is anticipated that newer generations will likely perform much better. © 2023 Elsevier Masson SAS
Authors & Co-Authors
Ghozy, Sherief A.
United States, Rochester
Mayo Clinic
United Kingdom, Oxford
University of Oxford
Azzam, Ahmed Y.
United States, Saint Paul
Saint Paul College
Kallmes, Kevin M.
United States, Saint Paul
Saint Paul College
Adusumilli, Gautam
United States, Palo Alto
Stanford University
Kadirvel, Ramanathan D.
United States, Rochester
Mayo Clinic
Kallmes, David F.
United States, Rochester
Mayo Clinic
Statistics
Citations: 3
Authors: 6
Affiliations: 6
Identifiers
Doi:
10.1016/j.neurad.2023.02.001
ISSN:
01509861
Research Areas
Genetics And Genomics
Noncommunicable Diseases
Study Approach
Qualitative
Quantitative
Systematic review