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Publication Details
AFRICAN RESEARCH NEXUS
SHINING A SPOTLIGHT ON AFRICAN RESEARCH
medicine
Long-term follow-up of living kidney donors: A longitudinal study
BJU International, Volume 100, No. 6, Year 2007
Notification
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Description
OBJECTIVE: To analyse retrospectively the general health status and renal and cardiovascular consequences of living-related kidney donation, as the long-term effects of unilateral nephrectomy for kidney donation are of particular interest with the currently increasing practice of living-donor transplantation. PATIENTS AND METHODS: Living-related kidney donors (1400) who had donated their kidneys between 1976 and 2002 were asked to attend a dedicated donor follow-up clinic starting in 2004. We attempted to contact all donors to determine the long-term outcome of their remaining kidney. All kidney donors who responded had a detailed assessment, and were questioned about rehabilitation and their feelings on donating a kidney. The data were compared to the age-matched health tables of the Egyptian general population. RESULTS: In all, 339 donors had a complete evaluation (mean age at the time of evaluation 47.8 years, sd 11; mean follow-up 10.7 years, sd 4.9). The mean (sd) creatinine level after donation was 1.1 (1.2) mg/dL, and creatinine clearance 109 (33) mL/min; the clearance was <60 mL/min in 0.9% of donors and proteinuria was >300 mg/24 h in 1.5% of donors. Seventy-five (22.1%) donors became hypertensive and the rate was higher in donors with an interval of >25 years from donation; 174 (51.3%) of patients became either overweight or obese. Diabetes mellitus developed in 23 (6.8%) and was more common in patients with significant weight gain. CONCLUSIONS: Donor nephrectomy has minimal adverse effects on overall health status. Regular donor follow-up identifies at-risk populations and potentially modifiable factors. © 2007 The Authors.
Authors & Co-Authors
El-Agroudy, Amgad Baz
Egypt, Mansoura
Mansoura University, Urology and Nephrology Center
Sabry, Alaa Abdelaziz
Egypt, Mansoura
Mansoura University, Urology and Nephrology Center
Wafa, Ehab Wahba
Egypt, Mansoura
Mansoura University, Urology and Nephrology Center
Neamatalla, Ahmed Hassan
Egypt, Mansoura
Mansoura University, Urology and Nephrology Center
Ismail, A. M.
Egypt, Mansoura
Mansoura University, Urology and Nephrology Center
Mohsen, T. A.
Egypt, Mansoura
Mansoura University, Urology and Nephrology Center
Khalil, Abd Allah
Egypt, Mansoura
Mansoura University, Urology and Nephrology Center
Shokeir, Ahmed Abdulrahman
Egypt, Mansoura
Mansoura University, Urology and Nephrology Center
Ghoneim, Mohamed A.
Egypt, Mansoura
Mansoura University, Urology and Nephrology Center
Statistics
Citations: 57
Authors: 9
Affiliations: 1
Identifiers
Doi:
10.1111/j.1464-410X.2007.07054.x
ISSN:
14644096
e-ISSN:
1464410X
Research Areas
Disability
Health System And Policy
Noncommunicable Diseases
Study Design
Cross Sectional Study
Cohort Study
Study Approach
Quantitative