Skip to content
Home
About Us
Resources
Profiles Metrics
Authors Directory
Institutions Directory
Top Authors
Top Institutions
Top Sponsors
AI Digest
Contact Us
Menu
Home
About Us
Resources
Profiles Metrics
Authors Directory
Institutions Directory
Top Authors
Top Institutions
Top Sponsors
AI Digest
Contact Us
Home
About Us
Resources
Profiles Metrics
Authors Directory
Institutions Directory
Top Authors
Top Institutions
Top Sponsors
AI Digest
Contact Us
Menu
Home
About Us
Resources
Profiles Metrics
Authors Directory
Institutions Directory
Top Authors
Top Institutions
Top Sponsors
AI Digest
Contact Us
Publication Details
AFRICAN RESEARCH NEXUS
SHINING A SPOTLIGHT ON AFRICAN RESEARCH
immunology and microbiology
Begomovirus 'melting pot' in the south-west Indian Ocean islands: Molecular diversity and evolution through recombination
Journal of General Virology, Volume 88, No. 12, Year 2007
Notification
URL copied to clipboard!
Description
During the last few decades, many virus species have emerged, often forming dynamic complexes within which viruses share common hosts and rampantly exchange genetic material through recombination. Begomovirus species complexes are common and represent serious agricultural threats. Characterization of species complex diversity has substantially contributed to our understanding of both begomovirus evolution, and the ecological and epidemiological processes involved in the emergence of new viral pathogens. To date, the only extensively studied emergent African begomovirus species complex is that responsible for cassava mosaic disease. Here we present a study of another emerging begomovirus species complex which is associated with serious disease outbreaks in bean, tobacco and tomato on the south-west Indian Ocean (SWIO) islands off the coast of Africa. On the basis of 14 new complete DNA-A sequences, we describe seven new island monopartite begomovirus species, suggesting the presence of an extraordinary diversity of begomovirus in the SWIO islands. Phylogenetic analyses of these sequences reveal a close relationship between monopartite and bipartite African begomoviruses, supporting the hypothesis. that either bipartite African begomoviruses have captured B components from other bipartite viruses, or there have been multiple B-Component losses amongst SWIO virus progenitors. Moreover, we present evidence that detectable recombination events amongst African, Mediterranean and SWIO begomoviruses, while substantially contributing to their diversity, have not occurred randomly throughout their genomes. We provide the first statistical support for three recombination hot-spots (V1/C3 interface, C1 centre and the entire IR) and two recombination cold-spots (the V2 and the third quarter of V1) in the genomes of begomoviruses. © 2007 SGM.
Authors & Co-Authors
Lefeuvre, Pierre F.
France, Saint-denis
Université de la Réunion
Martin, Darren Patrick
South Africa, Cape Town
University of Cape Town
Hoareau, Murielle
France, Saint-denis
Université de la Réunion
Nazé, Florence
France, Saint-denis
Université de la Réunion
Delatte, Hélène
France, Saint-denis
Université de la Réunion
Thierry, M.
France, Saint-denis
Université de la Réunion
Varsani, Arvind
South Africa, Cape Town
University of Cape Town
Becker, Nathalie
France, Paris
Museum National D'histoire Naturelle
Reynaud, Bernard
France, Saint-denis
Université de la Réunion
Lett, Jean Michel
France, Saint-denis
Université de la Réunion
Statistics
Citations: 179
Authors: 10
Affiliations: 3
Identifiers
Doi:
10.1099/vir.0.83252-0
ISSN:
00221317
Research Areas
Genetics And Genomics
Substance Abuse