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Publication Details
AFRICAN RESEARCH NEXUS
SHINING A SPOTLIGHT ON AFRICAN RESEARCH
agricultural and biological sciences
Drug efficacy of praziquantel and albendazole in school children in Mwea Division, Central Province, Kenya
Acta Tropica, Volume 102, No. 3, Year 2007
Notification
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Description
The objective of this research was to assess drug efficacy in school children after mass chemotherapy with praziquantel and albendazole conducted in Mwea Division, Kirinyaga District, Central Kenya in 2004. In total 2300 children aged between 4 and 18 years in five primary schools were selected for the study. Before mass chemotherapy, prevalence of infection was 47.4% for Schistosoma mansoni, 16.7% for Necator americanus, 1.6% for Ascaris lumbricoides, and 0.8% for Trichuris trichiura. Post-treatment stool examination was carried out 8 weeks later, and a total of 1942 stool samples were collected. Prevalence decreased to 8.6% for S. mansoni, 0.2% for N. americunus, 0 for A. lumbricoides, and 0.6% for T. trichiura. Efficacy was good for S. mansoni and N. americanus (92.6% and 95.0%, respectively). Results of the first round of treatment of school-age children in Mwea indicate a good reduction in parasite burden. © 2007 Elsevier B.V. All rights reserved.
Authors & Co-Authors
Kihara, Jimmy Hussein
Kenya, Nairobi
Ministry of Health Nairobi
Kenya, Nairobi
Kenya Medical Research Institute
Muhoho, Ngethe D.
Kenya, Nairobi
Kenya Medical Research Institute
Njomo, Doris Wairimu
Kenya, Nairobi
Kenya Medical Research Institute
Mwobobia, Isaac K.
Kenya, Nairobi
Kenya Medical Research Institute
Josyline, K.
Kenya, Nairobi
Kenya Medical Research Institute
Mitsui, Yoshinori
Kenya, Nairobi
Kenya Medical Research Institute
Awazawa, Toshiki
Kenya, Nairobi
Kenya Medical Research Institute
Amano, Teruaki
Kenya, Nairobi
Kenya Medical Research Institute
Mwandawiro, Charles Simiti
Kenya, Nairobi
Kenya Medical Research Institute
Statistics
Citations: 46
Authors: 9
Affiliations: 2
Identifiers
Doi:
10.1016/j.actatropica.2007.04.017
ISSN:
0001706X
Research Areas
Cancer
Maternal And Child Health
Study Design
Cross Sectional Study
Study Locations
Kenya