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Publication Details
AFRICAN RESEARCH NEXUS
SHINING A SPOTLIGHT ON AFRICAN RESEARCH
medicine
Opportunities and challenges for cost-efficient implementation of new point-of-care diagnostics for HIV and tuberculosis
Journal of Infectious Diseases, Volume 205, No. SUPPL. 2, Year 2012
Notification
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Description
Stakeholders agree that supporting high-quality diagnostics is essential if we are to continue to make strides in the fight against human immunodeficiency virus (HIV) and tuberculosis. Despite the need to strengthen existing laboratory infrastructure, which includes expanding and developing new laboratories, there are clear diagnostic needs where conventional laboratory support is insufficient. Regarding HIV, rapid point-of-care (POC) testing for initial HIV diagnosis has been successful, but several needs remain. For tuberculosis, several new diagnostic tests have recently been endorsed by the World Health Organization, but a POC test remains elusive. Human immunodeficiency virus and tuberculosis are coendemic in many high prevalence locations, making parallel diagnosis of these conditions an important consideration. Despite its clear advantages, POC testing has important limitations, and laboratory-based testing will continue to be an important component of future diagnostic networks. Ideally, a strategic deployment plan should be used to define where and how POC technologies can be most efficiently and cost effectively integrated into diagnostic algorithms and existing test networks prior to widespread scale-up. In this fashion, the global community can best harness the tremendous capacity of novel diagnostics in fighting these 2 scourges. © 2012 The Author.
Authors & Co-Authors
Schito, Marco L.
United States, Bethesda
National Institutes of Health Nih
Peter, Trevor F.
United States, Boston
Clinton Health Access Initiative, Inc.
Cavanaugh, Sean S.
United States, Atlanta
Centers for Disease Control and Prevention
Piatek, Amy S.
United States, Washington, D.c.
United States Agency for International Development
Young, Gloria J.
United States, Franklin Lakes
Becton, Dickinson and Company
Alexander, Heather L.
United States, Atlanta
National Center for Hiv, Viral Hepatitis, Std, and tb Prevention
Coggin, William
United States, Washington, D.c.
U.s. Department of State
Domingo, Gonzalo J.
United States, Seattle
Path Seattle
Ellenberger, Dennis L.
United States, Atlanta
National Center for Hiv, Viral Hepatitis, Std, and tb Prevention
Ermantraut, Eugen
Germany, Jena
Alere Technologies Gmbh
Jani, Ilesh Vinodrai
Mozambique, Maputo
Instituto Nacional de Saude Maputo
Katamba, Achilles
Uganda, Kampala
Makerere University
Palamountain, Kara M.
United States, Evanston
Kellogg School of Management Northwestern University
Essajee, Shaffiq M.
Switzerland, Geneva
Organisation Mondiale de la Santé
Dowdy, David W.
United States, Baltimore
Johns Hopkins Bloomberg School of Public Health
Statistics
Citations: 96
Authors: 15
Affiliations: 14
Identifiers
Doi:
10.1093/infdis/jis044
ISSN:
00221899
Research Areas
Infectious Diseases
Study Design
Cross Sectional Study