Skip to content
Home
About Us
Resources
Profiles Metrics
Authors Directory
Institutions Directory
Top Authors
Top Institutions
Top Sponsors
AI Digest
Contact Us
Menu
Home
About Us
Resources
Profiles Metrics
Authors Directory
Institutions Directory
Top Authors
Top Institutions
Top Sponsors
AI Digest
Contact Us
Home
About Us
Resources
Profiles Metrics
Authors Directory
Institutions Directory
Top Authors
Top Institutions
Top Sponsors
AI Digest
Contact Us
Menu
Home
About Us
Resources
Profiles Metrics
Authors Directory
Institutions Directory
Top Authors
Top Institutions
Top Sponsors
AI Digest
Contact Us
Publication Details
AFRICAN RESEARCH NEXUS
SHINING A SPOTLIGHT ON AFRICAN RESEARCH
pharmacology, toxicology and pharmaceutics
Some pharmacological properties of extracts of Terminalia sericea roots
Journal of Ethnopharmacology, Volume 97, No. 1, Year 2005
Notification
URL copied to clipboard!
Description
Terminalia sericea Burch. Ex. DC (Combretaceae) extracts are used to treat bacterial infections, diarrhea, and diabetes. Intermediate and polar extracts of the roots exhibited antibacterial activity against Staphylococcus aureus, Escherichia coli, Bacillus anthracis, and Pseudomonas aeruginosa, while the petroleum ether extract was inactive. The extracts were mildly active against Bacillus anthracis and Pseudomonas aeruginosa but exhibited the highest activity against Staphylococcus aureus. They also exhibited antifungal activity against Candida albicans and Aspergillus niger. An 80% aqueous ethanol extract of the roots did not have any effect on blood glucose levels during an oral glucose tolerance test (OGTT), in mice (P > 0.05). With the exception of the dichloromethane and petroleum ether extracts, all the intermediate and polar extracts were toxic to brine shrimps giving LC 50 (95% confidence intervals) values ranging from 5.4 (3.5-8.4) to 17.4 (11.4-26.5) μg/ml, while that of cyclophosphamide, a standard anticancer drug, was 16.3 (10.6-25.2) μg/ml. Further work is in progress to isolate and identify active compounds in the extracts. © 2004 Elsevier Ireland Ltd. All rights reserved.
Authors & Co-Authors
Moshi, Mainen Julius
Tanzania, Dar es Salaam
Muhimbili University of Health and Allied Sciences
Mbwambo, Zakaria H.
Tanzania, Dar es Salaam
Muhimbili University of Health and Allied Sciences
Statistics
Citations: 97
Authors: 2
Affiliations: 1
Identifiers
Doi:
10.1016/j.jep.2004.09.056
ISSN:
03788741
Research Areas
Environmental
Health System And Policy
Noncommunicable Diseases
Study Locations
Niger