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Publication Details
AFRICAN RESEARCH NEXUS
SHINING A SPOTLIGHT ON AFRICAN RESEARCH
medicine
A mixed-methods evaluation of adherence to preventive treatment among child tuberculosis contacts in Indonesia
International Journal of Tuberculosis and Lung Disease, Volume 20, No. 8, Year 2016
Notification
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Description
BACKGROUND: Tuberculosis (TB) can be prevented using isoniazid preventive therapy (IPT) among child contacts. However, the benefits of IPT depend on adherence to at least 6 months of daily treatment. A greater understanding of the barriers to and facilitators of adherence to IPT in resource-poor settings is required to optimise the benefits. METHODS : We prospectively evaluated adherence to IPT and its associated factors among child contacts (age 0-5 years) eligible for IPT. We undertook in-depth interviews with care givers and a focus group discussion with health careworkers,whichwere thematically analysed to explore barriers to and facilitators of adherence from the perspective of both care givers and health workers. RESULT S : Of 99 eligible children, 49 (49.5%) did not complete 6 months of IPT. Children whose care giver collected their IPT medications from primary health centres were more likely to have incomplete adherence than those who collected them from hospitals (aOR 2.9, 95%CI 1.1-7.8). Thematic analyses revealed major barriers to and facilitators of adherence: regimenrelated, care giver-related and health care-related factors, social support and access. Many of these factors are readily modifiable. CONCLUS ION: Providing information about IPT and improving accessibility for care givers to receive IPT at the primary health care facility should be priorities to facilitate implementation. © 2016 The Union.
Authors & Co-Authors
Triasih, Rina
Indonesia, Yogyakarta
Universitas Gadjah Mada
Australia, Melbourne
Royal Children's Hospital, Melbourne
Padmawati, Retna Siwi
Indonesia, Yogyakarta
Universitas Gadjah Mada
Duke, Trevor D.
Australia, Melbourne
Royal Children's Hospital, Melbourne
Robertson, Colin Francis
Australia, Melbourne
Royal Children's Hospital, Melbourne
Sawyer, Susan Margaret
Australia, Melbourne
Royal Children's Hospital, Melbourne
Australia, Melbourne
University of Melbourne
Graham, Stephen Michael
Australia, Melbourne
Royal Children's Hospital, Melbourne
France, Paris
International Union Against Tuberculosis and Lung Disease
Statistics
Citations: 18
Authors: 6
Affiliations: 4
Identifiers
Doi:
10.5588/ijtld.15.0952
ISSN:
10273719
Research Areas
Health System And Policy
Infectious Diseases
Maternal And Child Health
Study Approach
Qualitative