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Publication Details
AFRICAN RESEARCH NEXUS
SHINING A SPOTLIGHT ON AFRICAN RESEARCH
biochemistry, genetics and molecular biology
HPA polymorphism in sub-Saharan African populations: Beninese, Cameroonians, Congolese, and Pygmies
Tissue Antigens, Volume 65, No. 3, Year 2005
Notification
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Description
The frequency of human platelet antigen-1 (HPA-1) to HPA-11w (excluding HPA-8w) and HPA-15 systems was studied in four sub-Saharan populations: Beninese, Congolese (Democratic Republic of Congo Kinshasa), Cameroonians, and Aka pygmies (Central African Republic). No report of HPA prevalence has previously been published concerning these populations which are characterized by the highest HPA-2b gene frequencies of any reported to date (Aka 0.393, Benin 0.292, Cameroon 0.237, and Congo 0.224) and at lesser degree HPA-5b (Aka 0.405, Congo 0.268, Cameroon 0.254, and Benin 0.182). This study is of great importance (i) particularly in the context of the diversity caused by the population migrations, we may observe today in our hospitals (ii) to confirm that the Pygmy population with distinctive frequencies (absence of the HPA-1b, HPA-2b, and HPA-5b highest frequencies) is an isolated population. Copyright © Blackwell Munksgaard 2005.
Authors & Co-Authors
Hallé, Liliane
France, Paris
Institut National de la Transfusion Sanguine
Bigot, André K.
Benin, Cotonou
University of Abomey-calavi
Mulen-Imandy, G.
Cameroon, Douala
Hopital General de Douala
M'Bayo, K.
Democratic Republic Congo, Kinshasa
Clinique Universitaire de Kinshasa
Jaeger, G.
France, Paris
Centres Européens Associés de Biologie Humaine
Anani, Ludovic Y.
Benin, Cotonou
University of Abomey-calavi
Martageix, Corinne
France, Paris
Institut National de la Transfusion Sanguine
Bianchi, F.
France, Paris
Institut National de la Transfusion Sanguine
Julien, E.
France, Paris
Institut National de la Transfusion Sanguine
Kaplan, Cecíle G.
France, Paris
Institut National de la Transfusion Sanguine
Statistics
Citations: 50
Authors: 10
Affiliations: 5
Identifiers
Doi:
10.1111/j.1399-0039.2005.00360.x
ISSN:
00012815
Research Areas
Genetics And Genomics
Study Design
Cross Sectional Study
Study Locations
Benin
Cameroon
Central African Republic
Congo