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Publication Details
AFRICAN RESEARCH NEXUS
SHINING A SPOTLIGHT ON AFRICAN RESEARCH
biochemistry, genetics and molecular biology
PhytAMP: A database dedicated to antimicrobial plant peptides
Nucleic Acids Research, Volume 37, No. SUPPL. 1, Year 2009
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Description
Plants produce small cysteine-rich antimicrobial peptides as an innate defense against pathogens. Based on amino acid sequence homology, these peptides were classified mostly as α-defensins, thionins, lipid transfer proteins, cyclotides, snakins and hevein-like. Although many antimicrobial plant peptides are now well characterized, much information is still missing or is unavailable to potential users. The compilation of such information in one centralized resource, such as a database would therefore facilitate the study of the potential these peptide structures represent, for example, as alternatives in response to increasing antibiotic resistance or for increasing plant resistance to pathogens by genetic engineering. To achieve this goal, we developed a new database, PhytAMP, which contains valuable information on antimicrobial plant peptides, including taxonomic, microbiological and physicochemical data. Information is very easy to extract from this database and allows rapid prediction of structure/function relationships and target organisms and hence better exploitation of plant peptide biological activities in both the pharmaceutical and agricultural sectors. PhytAMP may be accessed free of charge at http://phytamp.pfba-lab.org. © 2008 The Author(s).
Authors & Co-Authors
Hammami, Riadh
Tunisia, Tunis
Institut Supérieur Des Sciences Biologiques Appliquées de Tunis
France, Villeneuve-d'ascq
Unité de Glycobiologie Structurale et Fonctionnelle Ugsf
Canada, Quebec
Institut Des Nutraceutiques et Des Aliments Fonctionnels, Canada
Ben Hamida, Jeannette
Tunisia, Tunis
Institut Supérieur Des Sciences Biologiques Appliquées de Tunis
Vergoten, Gérard
France, Villeneuve-d'ascq
Unité de Glycobiologie Structurale et Fonctionnelle Ugsf
Fliss, Ismaïl
Canada, Quebec
Institut Des Nutraceutiques et Des Aliments Fonctionnels, Canada
Statistics
Citations: 258
Authors: 4
Affiliations: 3
Identifiers
Doi:
10.1093/nar/gkn655
ISSN:
03051048
e-ISSN:
13624962
Research Areas
Genetics And Genomics