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Publication Details
AFRICAN RESEARCH NEXUS
SHINING A SPOTLIGHT ON AFRICAN RESEARCH
medicine
Early physical and psycho-educational rehabilitation in patients with coronary artery bypass grafting: A randomized controlled trial
Journal of Rehabilitation Medicine, Volume 51, No. 2, Year 2019
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Description
Objectives: Rehabilitation of patients following coronary artery bypass grafting (CABG) has been widely studied; however, research into early rehabilitation after CABG is sparse. The aim of this trial was to assess the impact of early rehabilitation, compared with usual care in patients following CABG. Design: Randomized controlled trial. Patients: A total of 326 patients treated with CABG. Methods: Patients treated with CABG were randomized 1:1 to 4 weeks of comprehensive early rehabilitation or usual care. The primary outcome was the Six Minute Walk Test (6MWT). Secondary outcomes were mental health and physical activity (Medical Outcome Study Short Form; SF-12); anxiety and depression (Hospital Anxiety and Depression Scale; HADS); physical and emotional scores; sleep (Pittsburgh Sleep Quality Index; PSQI); pain (Örebro Musculoskeletal Screening Questionnaire; ÖMSQ) and muscle endurance (Sit-To-Stand test). Results: Sixteen patients dropped out. No significant differences between groups in the primary outcome (6MWT) were found after 4 weeks (p=0.27). For secondary outcomes the odds ratio of HADS-D ≥8 decreased in favour of the experimental intervention (p=0.04). There was non-adherence to parts of the intervention. Per-protocol analysis showed differences between groups for the 6MWT (p=0.02) and the Sit-To-Stand test (p=0.046). Conclusion: In general, the intervention had no effect on the 6MWT, or secondary outcomes, except for depressive symptoms. However, in adherent participants, the intervention had a positive effect for the primary and several secondary outcomes. © 2019 Foundation of Rehabilitation Information.
Authors & Co-Authors
Højskov, Ida Elisabeth
Denmark, Copenhagen
Rigshospitalet
Denmark, Copenhagen
Københavns Professionshøjskole
Moons, Philip
Belgium, Leuven
Ku Leuven
Sweden, Gothenburg
Göteborgs Universitet
Egerod, Ingrid
Denmark, Copenhagen
Copenhagen University Hospital
Olsen, Peter Skov
Denmark, Copenhagen
Rigshospitalet
Thygesen, Lau Caspar
Denmark, Odense
Syddansk Universitet
Gluud, Christian N.
Denmark, Copenhagen
Copenhagen University Hospital
Lindschou, Jane
Denmark, Copenhagen
Copenhagen University Hospital
Kikkenborg Berg, Selina Kikkenborg
Denmark, Copenhagen
Rigshospitalet
Statistics
Citations: 23
Authors: 8
Affiliations: 8
Identifiers
Doi:
10.2340/16501977-2499
ISSN:
16501977
Research Areas
Disability
Health System And Policy
Mental Health
Study Design
Randomised Control Trial
Case-Control Study
Study Approach
Quantitative