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Large bowel obstruction from advanced prostate cancer in a 41-year-old: The role of genetic testing

South African Journal of Surgery, Volume 58, No. 3, Year 2020

Summary We report a rare presentation of an advanced prostate cancer (Gleason 10) in a 41-year-old man with complete large bowel obstruction relieved by loop colostomy. His young age prompted a search for a cause and genetic testing confirmed chromosome 10 PTEN deletion. His immediate family members were screened and counselled appropriately. This case outlines the role of genetic testing in young males with prostate cancer.

Jonosky, J. B.
1. South Africa, Johannesburg Helen Joseph Hospital
2. South Africa, Johannesburg Rahima Moosa Mother and Child Hospital
3. South Africa, Johannesburg University of the Witwatersrand Faculty of Health Sciences
de Villiers, Nico J.P.
1. South Africa Ampath Genetics
Wadee, Reubina
1. South Africa, Johannesburg University of the Witwatersrand
2. South Africa, Johannesburg National Health Laboratory Service
Chinegwundoh, Frank
1. United Kingdom, London Barts Health Nhs Trust
Adam, Ahmed
1. South Africa, Johannesburg Helen Joseph Hospital
2. South Africa, Johannesburg Rahima Moosa Mother and Child Hospital
3. South Africa, Johannesburg University of the Witwatersrand Faculty of Health Sciences

AFRICAN RESEARCH NEXUS

Large bowel obstruction from advanced prostate cancer in a 41-year-old: The role of genetic testing

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AFRICAN RESEARCH NEXUS

Large bowel obstruction from advanced prostate cancer in a 41-year-old: The role of genetic testing

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African Research Nexus

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