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Publication Details
AFRICAN RESEARCH NEXUS
SHINING A SPOTLIGHT ON AFRICAN RESEARCH
medicine
Global, Regional, and National Burden of Cardiovascular Diseases for 10 Causes, 1990 to 2015
Journal of the American College of Cardiology, Volume 70, No. 1, Year 2017
Notification
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Description
Background The burden of cardiovascular diseases (CVDs) remains unclear in many regions of the world. Objectives The GBD (Global Burden of Disease) 2015 study integrated data on disease incidence, prevalence, and mortality to produce consistent, up-to-date estimates for cardiovascular burden. Methods CVD mortality was estimated from vital registration and verbal autopsy data. CVD prevalence was estimated using modeling software and data from health surveys, prospective cohorts, health system administrative data, and registries. Years lived with disability (YLD) were estimated by multiplying prevalence by disability weights. Years of life lost (YLL) were estimated by multiplying age-specific CVD deaths by a reference life expectancy. A sociodemographic index (SDI) was created for each location based on income per capita, educational attainment, and fertility. Results In 2015, there were an estimated 422.7 million cases of CVD (95% uncertainty interval: 415.53 to 427.87 million cases) and 17.92 million CVD deaths (95% uncertainty interval: 17.59 to 18.28 million CVD deaths). Declines in the age-standardized CVD death rate occurred between 1990 and 2015 in all high-income and some middle-income countries. Ischemic heart disease was the leading cause of CVD health lost globally, as well as in each world region, followed by stroke. As SDI increased beyond 0.25, the highest CVD mortality shifted from women to men. CVD mortality decreased sharply for both sexes in countries with an SDI >0.75. Conclusions CVDs remain a major cause of health loss for all regions of the world. Sociodemographic change over the past 25 years has been associated with dramatic declines in CVD in regions with very high SDI, but only a gradual decrease or no change in most regions. Future updates of the GBD study can be used to guide policymakers who are focused on reducing the overall burden of noncommunicable disease and achieving specific global health targets for CVD. © 2017 The Authors
Available Materials
https://efashare.b-cdn.net/share/pmc/articles/PMC5491406/bin/mmc1.pdf
https://efashare.b-cdn.net/share/pmc/articles/PMC5491406/bin/mmc2.docx
Authors & Co-Authors
Roth, Gregory A.
United States, Seattle
University of Washington
Johnson, Catherine Owens
United States, Seattle
University of Washington
Abajobir, Amanuel Alemu
Australia, Brisbane
The University of Queensland
Abd-Allah, Foad
Egypt, Giza
Cairo University
Abera, Semaw Ferede
Ethiopia, Makale
Mekelle University
Abyu, Gebre Yitayih
Ethiopia, Makale
Mekelle University
Ahmed, Muktar Beshir
Ethiopia, Jimma
Jimma University
Aksut, Baran
United States, Cleveland
Cleveland Clinic Foundation
Alam, Tahiya
United States, Seattle
University of Washington
Alam, Khurshid
Australia, Melbourne
University of Melbourne
Alla, François F.
France, Nancy
Université de Lorraine
Alvis-Guzman, Nelson
Colombia, Cartagena
Universidad de Cartagena
Amrock, Stephen Marc
United States, Portland
Oregon Health & Science University
Ansari, Hossein
Iran, Zahedan
Zahedan University of Medical Sciences
Ärnlöv, Johan
Sweden, Uppsala
Uppsala Universitet
Asayesh, Hamid
Iran, Qom
Qom University of Medical Sciences and Health Services
Atey, Tesfay Mehari
Ethiopia, Makale
Mekelle University
Ávila-Burgos, Leticia Del Socorro
Mexico, Cuernavaca
Instituto Nacional de Salud Publica
Awasthi, Ashish
India, Lucknow
Sanjay Gandhi Postgraduate Institute of Medical Sciences
Banerjee, Amitava
United Kingdom, London
University College London
Barac, Aleksandra M.
Serbia, Belgrade
University of Belgrade
Bärnighausen, Till Winfried
United States, Cambridge
Harvard University
Barregård, Lars
Sweden, Gothenburg
Göteborgs Universitet
Bedi, Neeraj
Saudi Arabia, Jazan
Jazan University
Belay Ketema, Ezra
Ethiopia, Makale
Mekelle University
Bennett, Derrick A.
United Kingdom, Oxford
University of Oxford
Berhe, Gebremedhin
Ethiopia, Makale
Mekelle University
Bhutta, Zulfiqar A.
Pakistan, Karachi
The Aga Khan University
Bitew, Shimelash Bitew
Ethiopia, Sodo
Wolaita Sodo University
Carapetis, Jonathan Rhys
Australia, Perth
The University of Western Australia
Carrero, Juan Jesús
Sweden, Stockholm
Karolinska Institutet
Carvalho Malta, Deborah Carvalho
Brazil, Belo Horizonte
Universidade Federal de Minas Gerais
Castañeda-Orjuela, C. A.
Colombia, Bogota
Instituto Nacional de Salud
Castillo-Rivas, Jacqueline
Costa Rica, San Jose
Caja Costarricense de Seguro Social
Catalá-López, Ferrán
Spain, Madrid
Centro de Investigación Biomédica en Red de Salud Mental
Choi, Jee-young
South Korea, Seoul
Seoul National University Hospital
Christensen, Hanne Krarup
Denmark, Copenhagen
Bispebjerg Hospital
Cirillo, Massimo
Italy, Salerno
Università Degli Studi Di Salerno
Cooper, Leslie T.
United States, Rochester
Mayo Clinic
Criqui, Michael H.
United States, La Jolla
University of California, San Diego
Cundiff, David Keith
Unknown Affiliation
Damasceno, A. Antonio Moura
Mozambique, Maputo
Universidade Eduardo Mondlane
Dandona, Lalit
United States, Seattle
University of Washington
India, New Delhi
Public Health Foundation of India
Dandona, Rakhi
United States, Seattle
University of Washington
India, New Delhi
Public Health Foundation of India
Davletov, K.
Kazakhstan, Almaty
Scientific and Research Institute of Cardiology and Internal Diseases
Dharmaratne, Samath Dhamminda
Sri Lanka, Peradeniya
University of Peradeniya
Dorairaj, Prabhakaran
India, Gurgaon
Centre for Chronic Disease Control
Dubey, Manisha
India, Mumbai
International Institute for Population Sciences
Ehrenkranz, Rebecca C.
United States, Seattle
University of Washington
Zaki, Maysaa El S.
Egypt, Mansoura
Mansoura University
Faraon, Emerito Jose Aquino
Philippines, Manila
University of the Philippines Manila
Esteghamati, Alireza
Iran, Tehran
Tehran University of Medical Sciences
Farid, Talha A.
United States, Louisville
University of Louisville
Farvid, Maryam S.
United States, Cambridge
Harvard University
Feigin, Valery L.
New Zealand, Auckland
Auckland University of Technology
Ding, Eric L.
United States, Cambridge
Harvard University
Fowkes, Gerry R.
United Kingdom, Edinburgh
The University of Edinburgh
Gebrehiwot, Tsegaye Tewelde
Ethiopia, Jimma
Jimma University
Gillum, Richard Frank
United States, Cambridge
Harvard University
Gold, Audra L.
United States, Seattle
University of Washington
Gona, Philimon Nyakauru
United States, Boston
University of Massachusetts Boston
Gupta, Rajeev C.
India, Jaipur
Eternal Heart Care Centre and Research Institute
Habtewold, Tesfa Dejenie
Netherlands, Groningen
Rijksuniversiteit Groningen
Hafezi-Nejad, Nima
Iran, Tehran
Tehran University of Medical Sciences
Hailu, Tesfay Tekle
Ethiopia, Makale
Mekelle University
Hailu, Gessessew Bugssa
Ethiopia, Makale
Mekelle University
Hankey, Graeme J.
Australia, Perth
The University of Western Australia
Hassen, H. Y.
Ethiopia, Mizan Teferi
Mizan-tepi University
Abate, Kalkidan Hassen
Ethiopia, Jimma
Jimma University
Havmoeller, Rasmus J.
Sweden, Stockholm
Karolinska Institutet
Hay, Simon I.
United States, Seattle
University of Washington
United Kingdom, Oxford
University of Oxford
Horino, Masako
United States, Carson City
Nevada Division of Public and Behavioral Health
Hotez, Peter J.
United States, Houston
Baylor College of Medicine
Jacobsen, Kathryn H.
United States, Fairfax
George Mason University
James, Spencer Lewis
United States, Denver
Denver Health
Javanbakht, Mehdi
United Kingdom, Aberdeen
University of Aberdeen
Jeemon, Panniyammakal
India, Gurgaon
Centre for Chronic Disease Control
John, Denny
Unknown Affiliation
Jonas, Jost Bruno
Germany, Heidelberg
Universität Heidelberg
Kalkonde, Yogeshwar V.
Unknown Affiliation
Karimkhani, Chanté Aksut
United States, Cleveland
University Hospitals Case Medical Center
Kasaeian, Amir
Iran, Tehran
Tehran University of Medical Sciences
Khader, Yousef Saleh
Jordan, Irbid
Jordan University of Science and Technology
Khan, Abdur Rahman
United States, Louisville
University of Louisville
Khang, Young-ho
South Korea, Seoul
Seoul National University
Khera, Sahil
United States, Valhalla
New York Medical College
Khoja, Abdullah
Saudi Arabia, Riyadh
Al-imam Muhammad Ibn Saud Islamic University
Khubchandani, Jagdish
United States, Muncie
Ball State University
Kim, Daniel J.
United States, Boston
Northeastern University
Kolte, Dhaval S.
United States, Providence
Brown University
Kosen, Soewarta
Indonesia, Jakarta
Badan Penelitian Dan Pengembangan Kesehatan, Kementerian Kesehatan Republik Indonesia
Krohn, Kristopher J.
United States, Seattle
University of Washington
Kumar, G. Anil
India, New Delhi
Public Health Foundation of India
Kwan, Gene F.
United States, Boston
Boston University Chobanian & Avedisian School of Medicine
Lal, Dharmesh Kumar
India, New Delhi
Public Health Foundation of India
Larsson, Anders Olof
Sweden, Uppsala
Uppsala Universitet
Linn, Shai A.
Israel, Haifa
University of Haifa
Lopez, Alan D.
Australia, Melbourne
University of Melbourne
Lotufo, P. Andrade
Brazil, Sao Paulo
Universidade de São Paulo
El Razek, Hassan Magdy Abd
Egypt, Mansoura
Mansoura University
Malekzadeh, Reza
Iran, Tehran
Tehran University of Medical Sciences
Mazidi, Mohsen
China, Beijing
Chinese Academy of Sciences
Meier, Toni
Germany, Halle
Martin-luther-universität Halle-wittenberg
Meles, Kidanu Gebremariam
Ethiopia, Makale
Mekelle University
Mensah, George A.
United States, Bethesda
National Institutes of Health Nih
Meretoja, Atte P.
Australia, Melbourne
University of Melbourne
Mezgebe, Haftay Berhane
Ethiopia, Makale
Mekelle University
Miller, Ted R.
United States, Beltsville
Pacific Institute for Research and Evaluation
Mirrakhimov, Erkin
Kyrgyzstan, Bishkek
Kyrgyz State Medical Academy
Mohammed, Shafiu Abdullah
Nigeria, Zaria
Ahmadu Bello University
Moran, Andrew E.
United States, New York
Columbia University
Musa, Kamarul Imran
Malaysia, Minden
Universiti Sains Malaysia
Narula, Jagat P.
United States, New York
The Mount Sinai Hospital
Neal, Bruce Charles
Australia, Sydney
George Institute for Global Health
Ngalesoni, Frida Namnyak
Tanzania, Dar es Salaam
Ministry of Health and Social Welfare
Nguyen, Grant
United States, Seattle
University of Washington
Makhlouf-Obermeyer, Carla
Lebanon, Beirut
American University of Beirut
Owolabi, Mayowa O.
Nigeria, Ibadan
University of Ibadan
Patton, George C.
Australia, Melbourne
University of Melbourne
Pedro, João Mário
Portugal, Porto
Universidade do Porto
Qato, Dima M.
United States, Chicago
University of Illinois at Chicago
Qorbani, Mostafa
Iran, Karaj
Alborz University of Medical Sciences
Rahimi, Kazem
United Kingdom, Oxford
University of Oxford
Rai, Rajesh Kumar
India, Kolkata
Society for Health and Demographic Surveillance
Rawaf, Salman
United Kingdom, London
Imperial College London
Ribeiro, Antonio L.
Brazil, Belo Horizonte
Universidade Federal de Minas Gerais
Safiri, Saeid
Iran, Maragheh
Maragheh University of Medical Sciences
Salomon, Joshua A.
United States, Cambridge
Harvard University
Santos, I. S.
Brazil, Sao Paulo
Universidade de São Paulo
Santric-Milicevic, Milena M.
Serbia, Belgrade
University of Belgrade
Sartorius, Benn
South Africa, Durban
University of Kwazulu-natal
Schutte, Aletta E.
South Africa, Potchefstroom
North-west University
Sepanlou, Sadaf G.
Iran, Tehran
Tehran University of Medical Sciences
Shaikh, Masood Ali A.
Unknown Affiliation
Shishehbor, Mehdi H.
United States, Cleveland
Cleveland Clinic Foundation
Shore, Hirbo Roba
Ethiopia, Dire Dawa
Haramaya University
Silva, Diego Augusto Santos
Brazil, Florianopolis
Universidade Federal de Santa Catarina
Sobngwi, Eugène
Cameroon, Yaounde
Université de Yaoundé I
Stranges, S.
Luxembourg, Strassen
Luxembourg Institute of Health
Swaminathan, Soumya
India, New Delhi
Indian Council of Medical Research
Tabarés-Seisdedos, R. T.
Spain, Madrid
Centro de Investigación Biomédica en Red de Salud Mental
Tadele Atnafu, Niguse
Ethiopia, Mizan Teferi
Mizan-tepi University
Tesfay, Fisaha Haile
Ethiopia, Makale
Mekelle University
Thrift, Amanda G.
Australia, Clayton
Monash University
Topoŕ-Ma̧dry, Roman
Poland, Krakow
Jagiellonian University Medical College
Truelsen, Thomas Clement
Denmark, Copenhagen
Københavns Universitet
Tyrovolas, Stefanos
Spain, Madrid
Centro de Investigación Biomédica en Red de Salud Mental
Ukwaja, Kingsley Nnanna
Nigeria, Abakaliki
Federal Teaching Hospital
Uthman, Olalekan A.
United Kingdom, Coventry
University of Warwick
Vasankari, T.
Finland, Tampere
Ukk Institute Finland
Vlassov, Vasily V.
Russian Federation, Moscow
Hse University
Vollset, Stein Emil
Norway, Oslo
Folkehelseinstituttet
Wakayo, Tolassa
Ethiopia, Jimma
Jimma University
Watkins, David Alan
United States, Seattle
University of Washington
Weintraub, Robert G.
Australia, Melbourne
Royal Children's Hospital, Melbourne
Werdecker, Andrea
Germany, Wiesbaden
Federal Institute for Population Research
Westerman, Ronny
Germany, Wiesbaden
Federal Institute for Population Research
Wiysonge, Charles Shey
South Africa, Tygerberg
Research in Southern Africa
Wolfe, Charles Da
United Kingdom, London
King's College London
Workicho, Abdulhalik
Ethiopia, Jimma
Jimma University
Yano, Yuichiro
United States, Evanston
Northwestern University
Yip, Paul Siu Fai
Hong Kong, Hong Kong
The University of Hong Kong
Younis, Mustafa Zeedan
United States, Jackson
Jackson State University
Yu, Chuanhua
China, Wuhan
Wuhan University
Vos, Theo
United States, Seattle
University of Washington
Naghavi, Mohsen
United States, Seattle
University of Washington
Murray, Christopher J.L.
United States, Seattle
University of Washington
Statistics
Citations: 2,661
Authors: 167
Affiliations: 113
Identifiers
Doi:
10.1016/j.jacc.2017.04.052
ISSN:
07351097
Research Areas
Disability
Noncommunicable Diseases
Sexual And Reproductive Health
Study Design
Cross Sectional Study
Cohort Study
Participants Gender
Male
Female