Acute Kidney Injury Among Children Likely Associated with Diethylene Glycol-Contaminated Medications — The Gambia, June–September 2022

What is already known about this topic? Diethylene glycol (DEG)-contaminated medications present a global health threat, especially in low-income countries. What is added by this report? A large cluster of acute kidney injury cases affecting children in The Gambia in 2022 was associated with case fatality rates >80%. The implicated syrup-based pediatric medications that had been administered to patients were imported from a single Indian manufacturer. This is one of the first documented DEG outbreaks in which contaminated medications were imported rather than being domestically manufactured. What are the implications for public health practice? DEG mass poisonings continue to occur worldwide, especially in low-resource settings. Strengthened international pharmaceutical regulatory structures and event-based surveillance systems can help prevent DEG-associated large-scale poisoning events.