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Publication Details
AFRICAN RESEARCH NEXUS
SHINING A SPOTLIGHT ON AFRICAN RESEARCH
chemistry
Comparative study of chemical constituents of rhubarb from different origins
Chemical and Pharmaceutical Bulletin, Volume 54, No. 11, Year 2006
Notification
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Description
A comparative study of the pharmacologically active constituents of 24 rhubarb samples, which were identified genetically as Rheum tanguticum, 3 intraspecies groups of R. palmatum and R. officinale, was conducted using reversed-phase high performance liquid chromatography (HPLC) methods. Thirty compounds belonging to anthraquinones, anthraquinone glucosides, dianthrones, phenylbutanones, stilbenes, flavan-3-ols, procyanidins, galloylglucoses, acylglucoses, gallic acid, and polymeric procyanidins were analyzed quantitatively. The drug samples derived from the same botanical source showed similar chromatographic profiles, and the comparable specific shape that appeared in the 10-directed radar graphs constructed on the basis of the results of quantitative analysis indicated the relationship between chemical constituent patterns and genetic varieties of rhubarb samples. © 2006 Pharmaceutical Society of Japan.
Authors & Co-Authors
Komatsu, Katsuko
Japan, Toyama
University of Toyama
Nagayama, Yorinobu
Japan, Toyama
University of Toyama
Tanaka, Ken
Japan, Toyama
University of Toyama
Ling, Yun
China, Beijing
Beijing Yanjing Hospital
Cai, Shaoqing
China, Beijing
Peking University Health Science Center
Omote, Takayuki
Japan, Toyama
University of Toyama
Meselhy, M. R.
Egypt, Cairo
Faculty of Pharmacy
Statistics
Citations: 43
Authors: 7
Affiliations: 4
Identifiers
Doi:
10.1248/cpb.54.1491
ISSN:
00092363
e-ISSN:
13475223
Research Areas
Genetics And Genomics
Study Approach
Quantitative