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Publication Details
AFRICAN RESEARCH NEXUS
SHINING A SPOTLIGHT ON AFRICAN RESEARCH
medicine
Effects of honey, sucrose and glucose on blood glucose and C-peptide in patients with type 1 diabetes mellitus
Complementary Therapies in Clinical Practice, Volume 19, No. 1, Year 2013
Notification
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Description
This study was a case control cross sectional study that was conducted on 50 patients with type 1 diabetes mellitus and 30 controls without diabetes. The mean age of patients was 10.02 years. Oral sugar tolerance tests using glucose, sucrose and honey and measurement of fasting and postprandial serum C-peptide levels were done for all subjects in three separate sittings. The glycemic index (GI) and the peak incremental index (PII) were then calculated for each subject. Honey, compared to sucrose, had lower GI and PII in both patients and controls (P < 0.01). In both patients and controls, the increase in the level of C-peptide after honey was significant when compared with either glucose or sucrose (P < 0.01). Conclusion: Because of its possible stimulatory effect on diseased beta cells, honey might be considered in future therapeutic trials targeting beta cells of pancreas. © 2012 Elsevier Ltd.
Authors & Co-Authors
Abdulrhman, Mamdouh Abdulmaksoud
Egypt, Cairo
Faculty of Medicine - Ain Shams University
El-Hefnawy, Mohamed Hesham Fahmy
Egypt, Cairo
National Institute of Diabetes
Aly, R. H.
Egypt, Cairo
Faculty of Medicine - Ain Shams University
Abdel Hamid, Iman
Egypt, Cairo
Faculty of Medicine - Ain Shams University
Abou El-Goud, Ahmad
Egypt, Cairo
Faculty of Medicine - Ain Shams University
Refai, Doaa
Egypt, Cairo
Faculty of Medicine - Ain Shams University
Statistics
Citations: 35
Authors: 6
Affiliations: 2
Identifiers
Doi:
10.1016/j.ctcp.2012.08.002
ISSN:
17443881
Research Areas
Health System And Policy
Noncommunicable Diseases
Study Design
Cross Sectional Study
Case-Control Study