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Publication Details
AFRICAN RESEARCH NEXUS
SHINING A SPOTLIGHT ON AFRICAN RESEARCH
medicine
Distribution of COPD-related symptoms in the Middle East and North Africa: Results of the BREATHE study
Respiratory Medicine, Volume 106, No. SUPPL. 2, Year 2012
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Description
Chronic obstructive pulmonary disease (COPD) is a major cause of morbidity and mortality worldwide. However, its epidemiology in many developing countries is poorly characterised. The objective of this analysis was to evaluate respiratory symptoms which could be COPD-related in a large sample of individuals aged ≥40 years in ten countries in the Middle East and North Africa (Algeria, Egypt, Jordan, Lebanon, Morocco, Saudi Arabia, Syria, Tunisia, Turkey and United Arab Emirates), together with Pakistan, using a standardised methodology. A random sample of 457,258 telephone numbers was contacted. A screening questionnaire was administered to each eligible participant, which included six questions relating to respiratory symptoms. Of 65,154 eligible subjects, 62,086 agreed to participate and 61,551 provided usable data. The age- and gender-adjusted prevalence of symptoms (persistent productive cough or breathlessness or both) was 14.3% [95% CI: 14.0-14.6%], ranging from 7.2% in UAE to 19.1% in Algeria. Symptoms were more frequent (p < 0.0001) in women (16.7%) than in men (12.2%). The adjusted prevalence of COPD according to the "epidemiological" definition (symptoms or diagnosis and cigarette use ≥10 pack·years) was 3.6% [95% CI: 3.5-3.7%] (range: 1.9% in UAE to 6.1% in Syria). COPD was more frequent (p < 0.0001) in men (5.2%) than in women (1.8%). The frequency of symptoms was significantly higher in cigarette smokers (p< 0.001), as well as in waterpipe users (p < 0.026). In conclusion, the prevalence of COPD in this region seems to be lower than that reported in industrialised countries. Under-reporting and risk factors other than smoking may contribute to this difference. © 2012 Elsevier Ltd.
Authors & Co-Authors
Tageldin, Mohamed Awad
Egypt, Cairo
Ain Shams University
Nafti, Salim
Algeria, Algiers
Centre Hospitalo-universitaire de Mustapha Bacha
Khan, Javaid Ahmed
Pakistan, Karachi
The Aga Khan University Hospital
Nejjari, Chakib
Morocco, Fez
Université Sidi Mohamed Ben Abdellah
Béji, Majed
Tunisia, Tunis
Faculté de Médecine de Tunis
Mahboub, Bassam H.
United Arab Emirates, Sharjah
University of Sharjah
Obeidat, Nathir
Jordan, Amman
The University of Jordan
Uzaslan, Esra
Turkey, Bursa
Bursa Uludağ Üniversitesi
Sayiner, Abdullah
Turkey, Izmir
Ege Üniversitesi
Wali, Siraj Omar
Saudi Arabia, Jeddah
King Abdulaziz University
Rashid, Nauman
United Arab Emirates, Dubai
Glaxosmithkline, Uae
El-Hasnaoui, Abdelkader
United Arab Emirates, Dubai
Glaxosmithkline, Uae
Statistics
Citations: 122
Authors: 12
Affiliations: 11
Identifiers
Doi:
10.1016/S0954-6111(12)70012-4
ISSN:
09546111
e-ISSN:
15323064
Research Areas
Noncommunicable Diseases
Substance Abuse
Study Design
Cross Sectional Study
Study Locations
Multi-countries
Algeria
Egypt
Morocco
Tunisia
Participants Gender
Male
Female