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Publication Details
AFRICAN RESEARCH NEXUS
SHINING A SPOTLIGHT ON AFRICAN RESEARCH
immunology and microbiology
A survey of the management, control, and complications of diabetes mellitus in patients attending a diabetes clinic in Blantyre, Malawi, an area of high HIV prevalence
American Journal of Tropical Medicine and Hygiene, Volume 83, No. 3, Year 2010
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Description
The aim of this study was to describe the current status of diabetes care in an urban diabetes clinic in Malawi and the prevalence of human immunodeficiency virus (HIV) in this population, investigating possible associations between HIV and diabetes. A systematic prospective survey of patients attending the diabetes clinic at a teaching hospital in Blantyre, Malawi was conducted. Six hundred twenty patients were assessed. Seventy-four percent had glycosylated hemoglobin (HbA1C) > 7.5%. Systolic blood pressure was > 140 mm Hg in 52% of patients. Hypertension was more common in patients with raised creatinine (P < 0.003), retinopathy (P = 0.01), and stroke (P < 0.0002). Microvascular complication rates were high, specifically nephropathy (34.7%), retinopathy (34.7%), and neuropathy (46.4%). HIV seroprevalence was 13.7%. HIV-positive subjects had a lower body mass index (BMI) and lower fasting blood sugar, and they were more likely to have albuminuria (48.0% versus 33.3%; P < 0.05). Control of glycemia and hypertension were poor, and microvascular complications were common. Nephropathy in diabetic patients may be affected by HIV status. Copyright © 2010 by The American Society of Tropical Medicine and Hygiene.
Authors & Co-Authors
Cohen, Daniëlle
Malawi, Zomba
University of Malawi
Allain, Theresa Jane
Malawi, Zomba
University of Malawi
Glover, Simon J.
Malawi, Zomba
University of Malawi
Chimbayo, Daniel
Malawi, Zomba
University of Malawi
Dzamalala, Helen
Malawi, Zomba
University of Malawi
Hofland, Helma W.Chr
Malawi, Zomba
University of Malawi
Banda, Ndaziona Peter Kwanjo
Malawi, Zomba
University of Malawi
Zijlstra, Eduard Evert
Malawi, Zomba
University of Malawi
Statistics
Citations: 58
Authors: 8
Affiliations: 1
Identifiers
Doi:
10.4269/ajtmh.2010.10-0104
ISSN:
00029637
Research Areas
Health System And Policy
Infectious Diseases
Noncommunicable Diseases
Study Design
Cross Sectional Study
Cohort Study
Study Approach
Quantitative
Study Locations
Malawi